TBKBP1 antibody
Principal name
TBKBP1 antibody
Alternative names for TBKBP1 antibody
TBK1-binding protein 1, KIAA0775, Sintbad, ProSAPiP2, TANK-binding kinase 1-binding protein 1
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)
Background of TBKBP1 antibody
Prosapip2 (TBKBP1) is essential for signal transduction during viral infection thus plays a major role in the TNF/NF-kappaB pathway. It is an adaptor protein that constitutively binds TBK1 (TANK-binding kinase) and IKBKE and may play a role in antiviral innate immunity. Prosapip2 is a 615 amino acid adaptor protein belonging to the fibrillar collagen family, consisting of trimers of identical alpha 1 chains which are linked to each other by interchain disulfide bonds. It has a ubiquitous expression with highest levels in ovary, followed by the neuronal system. Prosapip2 binds to TBK1 and helps in the activation of IRF3 which controls the expression of antiviral genes during infection. Recent studies show that Prosapip2 is an interaction partner of ProSAP2/Shank3 and actin, suggesting a role as a linker molecule between postsynaptic density and the cytoskeleton.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA306842 | TBKBP1 antibody |
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| Rabbit Polyclonal Prosapip2 Antibody | |||||||
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Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, P, WB |
0.1 mg /
€415.00
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| OriGene Technologies, Inc. | |||||||
 +2 additional images |
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| TA336976 | TBKBP1 antibody |
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| Rabbit Polyclonal TBKBP1 Antibody | |||||||
![Western Blot: TBKBP1 Antibody [TA336976] - Western blot analysis of TBKBP1 in human brain lysate in the 1) absence and 2) presence of immunizing peptide 3) mouse brain and 4) rat brain using TA336976 at 4.0 ug/ml, 0.5 ug/ml and 1.0 ug/ml, respectively. No](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NBP2-24465-1-W.jpg) |
Rabbit | Purified | Hu, Ms, Rt | P, WB |
0.1 mg /
€335.00
|
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| OriGene Technologies, Inc. | |||||||
| +1 additional image |
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP323867 | TBKBP1 |
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| Recombinant protein of human TBK1 binding protein 1 (TBKBP1) | |||||
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Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
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|
| OriGene Technologies, Inc. | |||||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR209269L2V | Lenti ORF particles, Tbkbp1 (GFP-tagged) - Mouse TBK1 binding protein 1 (Tbkbp1), 200 uL, >10^7 TU/mL |
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200 µl /
€1,340.00
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| OriGene Technologies, Inc. | ||
| MR209269L1V | Lenti ORF particles, Tbkbp1 (Myc-DDK-tagged) - Mouse TBK1 binding protein 1 (Tbkbp1), 200 uL, >10^7 TU/mL |
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200 µl /
€1,200.00
|
|
| OriGene Technologies, Inc. | ||