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TBX1 antibody

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Principal name

TBX1 antibody

Alternative names for TBX1 antibody

T-box protein 1, T-box transcription factor TBX1, Testis-specific T-box protein

SwissProt ID

O43435 (Human), P70323 (Mouse), Q8AXX2 (Danre)

Gene ID

6899 (TBX1), 21380 (Tbx1)

Ncbi ID

NP_542378, NP_005983.1, NP_542377, NM_080646, NP_005983, NP_035662.1, NM_011532, NM_080647

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), GP (Guinea Pig), Rb (Rabbit), Eq (Equine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of TBX1 antibody

TBX1 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX1 product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where TBX1 has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

General readings

Yamagishi,H., et al., (2003) Genes Dev. 17 (2), 269-281

ARP33399_T100 - TBX1
Human kidney; TBX1 antibody - C-terminal region (ARP33399_T100) in Human kidney cells using Immunohistochemistry
ARP33399_T100 - TBX1
Human Jurkat; WB Suggested Anti-TBX1 Antibody Titration: 5.0ug/ml. Positive Control: Jurkat cell lysate; TBX1 antibody - C-terminal region (ARP33399_T100) in Human Jurkat cells using Western Blot
AP06637PU-N - TBX1
Western blot (WB) analysis of TBX1 antibody (Cat.-No.: AP06637PU-N) in extracts from COLO 205 cells.
ARP33398_P050 - TBX1
Human Lung; WB Suggested Anti-TBX1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Human Lung; TBX1 antibody - middle region (ARP33398_P050) in Human Lung cells using Western Blot
C10102-1 - TBX1
Immunofluorescence analysis of A549 cells, using TBX1 Antibody. The picture on the right is treated with the synthesized peptide.
C10102-1 - TBX1
Western blot analysis of extracts from COLO205 cells, using TBX1 Antibody. The lane on the right is treated with the synthesized peptide.
TA507326 - TBX1
Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-TBX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA507326)
TA507326 - TBX1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TBX1 (RC214605, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TBX1.
TP314605 - TBX1
TP316204 - TBX1
TA314594 - TBX1
Western blot analysis of extracts from COLO205 cells, using TBX1 antibody.The lane on the right is treated with the synthesized peptide.
TA314594 - TBX1
Immunofluorescence analysis of A549 cells, using TBX1 antibody.The picture on the right is treated with the synthesized peptide.
TA325103 - TBX1
TBX1 Antibody (C-term) (Cat.# TA325103) western blot analysis in HLVEC cell line lysates (35ug/lane).This demonstrates the TBX1 antibody detected the TBX1 protein (arrow).
TA325103 - TBX1
Western blot analysis of lysate from HLVEC cell line, using TBX1 Antibody (C-term) (Cat. #TA325103). TA325103 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
TA325103 - TBX1
Formalin-fixed and paraffin-embedded human testis tissue reacted with TBX1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
TA325103 - TBX1
IF image of A2058 cell stained with TBX1 Antibody (C-term)(Cat#TA325103). A2058 cells were incubated with TBX1 primary antibody (1:25, 1 h at 37?). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7 units/ml). Nuclei were counterstained with DAPI (blue) . TBX1 immunoreactivity is localized to nucleus significantly.
TA333561 - TBX1
WB Suggested Anti-TBX1 Antibody Titration: 5.0 ug/ml; Positive Control: Jurkat cell lysate
TA333561 - TBX1
Human kidney
TA333562 - TBX1
WB Suggested Anti-TBX1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Lung
TA347536 - TBX1
Western blot analysis on COLO205 cell lysate using TBX1 Antibody
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8 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TBX1 (C-term) antibody
  Rabbit polyclonal TBX1 Antibody (C-term)  
TBX1 Antibody (C-term) (Cat.# TA325103) western blot analysis in HLVEC cell line lysates (35ug/lane).This demonstrates the TBX1 antibody detected the TBX1 protein (arrow). Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €415.00
  OriGene Technologies, Inc.
+3 additional images

Highly validated antibody!

TBX1 antibody
  Rabbit polyclonal anti-TBX1 antibody  
Western blot analysis of extracts from COLO205 cells, using TBX1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

TBX1 antibody
  Rabbit Polyclonal Anti-TBX1 Antibody  
Western blot analysis on COLO205 cell lysate using TBX1 Antibody Rabbit IgG Purified Hu WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

TBX1 antibody
  TBX1 mouse monoclonal antibody, clone OTI1C2 (formerly 1C2)  
Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-TBX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA507326) Mouse IgG1 OTI1C2 Purified Hu P, WB
0.1 ml / €360.00
  OriGene Technologies, Inc.
+1 additional image

TrueMAB

TBX1 antibody
Western blot (WB) analysis of TBX1 antibody (Cat.-No.: AP06637PU-N) in extracts from COLO 205 cells. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TBX1 (transcript variant A)
  Recombinant protein of human T-box 1 (TBX1), transcript variant A  
TBX1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

TBX1 (transcript variant C)
  Purified recombinant protein of Homo sapiens T-box 1 (TBX1), transcript variant C  
TBX1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

Lysates

Catalog No.    

TBX1 overexpression lysate
TBX1 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

8 Item(s)

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Available Filters

Product Type
  1. Lysate (1)
  2. Primary Antibody (5)
  3. Protein | Growth Factor (2)
Clonality
  1. Polyclonal (4)
  2. Monoclonal (1)
Target
  1. TBX1 (7)
Property
  1. C-term (1)
Reactivity
  1. Human (Hu) (5)
Applications
  1. Western blot / Immunoblot (WB) (5)
  2. Paraffin Sections (P) (3)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  4. Enzyme Immunoassay (E) (1)
Presentation
  1. Purified (3)
  2. Aff - Purified (2)
Host
  1. Rabbit (4)
  2. Mouse (1)
Images
  1. 1 image (7)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (5)
  2. Immunofluorescence (IF) (2)
  3. IHC (1)
  4. Paraffin Sections (P) (1)
Species (Protein)
  1. Human (2)
Source
  1. HEK293 cells (2)
Manufacturer
  1. OriGene Technologies (8)
Service
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