TCR V beta 7 antibody
Principal name
TCR V beta 7 antibody
Alternative names for TCR V beta 7 antibody
T Cell Receptor V beta 7
Available reactivities
Available hosts
Available applications
Flow Cytometry (F), Immunoprecipitation (IP)
Background of TCR V beta 7 antibody
The TR310 antibody reacts with the mouse T cell receptor V beta7 segment . T cells expressing the alpha/ beta T cell receptor use clonally distributed TCRs to recognize cell-bound antigens such as peptide/MHC complexes and viral superantigens. The alpha/ beta TCR is an oligomeric TCR complex composed of covalently bound alpha and beta chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3 delta, gamma, epsilon, and zeta chains. The TR310 antibody reacts with one such clonally distributed TCR beta chain known as V beta7. V beta7 is expressed on a small subpopulation of both CD4+ and CD8+ T cells. The TR310 antibody has been used for the identification of V beta7 expressing T cells by flow cytometry and immunoprecipitation.
