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TGFBR2 antibody

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Principal name

TGFBR2 antibody

Alternative names for TGFBR2 antibody

TGF-beta receptor type-2, TGF-beta receptor type II, TGF-beta type II receptor, TbetaR-II, TGFR-2, Transforming growth factor-beta receptor type II

SwissProt ID

P37173 (Human), P38438 (Rat), P38551 (Pig), Q62312 (Mouse), Q90999 (Chick)

Gene ID

7048 (TGFBR2), 396399, 21813 (Tgfbr2), 81810

Ncbi ID

NP_001020018.1, 9606, NP_990759.1, NP_003233, NP_001020018, NP_003233.2, NM_001024847, NP_033397.3, BC052629, NM_031132, NM_003242

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Chk (Chicken), Bov (Bovine), Por (Porcine), Rb (Rabbit), Mky (Monkey), Gt (Goat)

Available hosts

Goat, Mouse, Rabbit, Sheep, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TGFBR2 antibody

TGFBR2 is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in its gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors.This gene is a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. It encodes a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein and binds TGF-beta. This receptor/ligand complex phosphorylates proteins which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

General readings

Song,K., (2006) J. Biol. Chem. 281 (12), 7765-7774

H00007048-A01 - TGFBR2
TGFBR2 polyclonal antibody (A01), Lot # 060525JCSI. Western Blot analysis of TGFBR2 expression in Raw 264.7.
AP06349PU-N - TGFBR2
Western blot analysis of TGF BR2 antibody (Cat.-No.: AP06349PU-N) in extracts from HepG2 cells(65K) or LOVO cells(100K).
ARP44743_T100 - TGFBR2
Human HepG2; WB Suggested Anti-TGFBR2 Antibody Titration: 5.0ug/ml. Positive Control: HepG2 cell lysate. TGFBR2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells.; TGFBR2 antibody - N-terminal region (ARP44743_T100) in Human HepG2 cells using Western Blot
AP20273PU-N - TGFBR2
Immunohistochemistry analyzes of AP20273PU-N TGFBR2 antibody in paraffin-embedded Human brain tissue.
AP20273PU-N - TGFBR2
Western blot analysis of AP20273PU-N TGFBR2 antibody in extracts from NIH/3T3 cells.
A1127-1 - TGFBR2
Immunohistochemistry analysis of paraffin-embedded human brain, using TGF beta Receptor II (Phospho-Ser225/250) Antibody. The picture on the right is treated with the synthesized peptide.
B1127-1 - TGFBR2
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TGF beta Receptor II (Ab-250) Antibody. The picture on the right is treated with the synthesized peptide.
B1127-1 - TGFBR2
Western blot analysis of extracts from NIH-3T3 cells, using TGF beta Receptor II (Ab-250) Antibody. The lane on the right is treated with the synthesized peptide.
C0338-1 - TGFBR2
Western blot analysis of extracts from HepG2 (65K) cells, using TGF beta Receptor II Antibody. The lane on the right is treated with the synthesized peptide.
AP55729PU-S - TGFBR2
Immunohistochemical analysis of paraffin-embedded human brain tissue using TGF β Receptor II (Phospho-Ser225/250) antibody AP55729PU-N (left)or the same antibody preincubated with blocking peptide (right).
CPA2158-100ul - TGFBR2
Western blot analysis of TGFBR2 expression in HepG2 (A); A549 (B); TF1 (C); KNRK (D) whole cell lysates.
CPA3336-100ul - TGFBR2
Western blot analysis of TGFBR2 (pS225) expression in A549 (A); NIH3T3L1 (B); KNRK (C); HepG2 (D) whole cell lysates.
TA590153 - TGFBR2
ELISA: TGF beta Receptor II Antibody
TP319855 - TGFBR2
TA311643 - TGFBR2
Western blot analysis of extracts from NIH/3T3 cells, using TGFBR2 (Ab-250) antibodyThe lane on the right is treated with the synthesized peptide.
TA311643 - TGFBR2
Immunohistochemistry analysis of paraffin-embedded human brain tissue using TGFBR2 (Ab-250) antibodyThe picture on the right is treated with the synthesized peptide.
TA314619 - TGFBR2
Western blot analysis of extracts from HepG2 cells, using TGF ß Receptor II antibody (#TA314619).The lane on the right is treated with the synthesized peptide.
TA319109 - TGFBR2
Western blot analysis of TGF-beta Receptor II in rat kidney tissue lysate.
TA324439 - TGFBR2
TGFBR2 Antibody (N-term) (Cat. #TA324439) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the TGFBR2 antibody detected the TGFBR2 protein (arrow).
TA324439 - TGFBR2
TGFBR2 Antibody (N-term) (Cat. #TA324439)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TGFBR2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
TA324439 - TGFBR2
Confocal immunofluorescent analysis of TGFBR2 Antibody (N-term) (Cat#TA324439) with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
TA332398 - TGFBR2
Western blot analysis of extracts of various cell lines, using TGFBR2 antibody.
TA332398 - TGFBR2
Immunofluorescence analysis of U20S cell using TGFBR2 antibody. Blue: DAPI for nuclear staining.
TA335780 - TGFBR2
WB Suggested Anti-TGFBR2 Antibody Titration: 5.0 ug/ml; Positive Control: HepG2 cell lysate.TGFBR2 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells
TA347477 - TGFBR2
Western blot analysis on NIH-3T3 cell lysate using TGFR2 Antibody

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TGFBR2 antibody
  Rabbit polyclonal TGFBR2 (Ab-250) antibody  
Western blot analysis of extracts from NIH/3T3 cells, using TGFBR2 (Ab-250) antibodyThe lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

TGFBR2 antibody
  Rabbit polyclonal TGF beta Receptor II antibody  
Western blot analysis of extracts from HepG2 cells, using TGF ß Receptor II antibody (#TA314619).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

TGFBR2 antibody
  Rabbit polyclonal anti-TGF-beta Receptor II antibody  
Western blot analysis of TGF-beta Receptor II in rat kidney tissue lysate. Rabbit Purified Hu, Ms, Rt P, WB
0.1 mg / €355.00
  OriGene Technologies, Inc.

TGFBR2 (N-term) antibody
  Rabbit polyclonal TGFBR2 Antibody (N-term)  
TGFBR2 Antibody (N-term) (Cat. #TA324439) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the TGFBR2 antibody detected the TGFBR2 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms ICC/IF, P, WB
0.4 ml / €415.00
  OriGene Technologies, Inc.
+2 additional images

TGFBR2 antibody
  Rabbit anti-TGFBR2 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using TGFBR2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €335.00
  OriGene Technologies, Inc.
+1 additional image

TGFBR2 antibody
  Rabbit Polyclonal Anti-TGFR2 Antibody  
Western blot analysis on NIH-3T3 cell lysate using TGFR2 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

TGFBR2 (27-85) antibody
TGFBR2 Sheep IgG Purified Chk C
50 µg / €400.00
  OriGene Technologies GmbH

TGFBR2 (77-148) antibody
TGFBR2 Sheep IgG Purified Chk C
0.1 mg / €400.00
  OriGene Technologies GmbH

TGFBR2 antibody
Western blot analysis of TGF BR2 antibody (Cat.-No.: AP06349PU-N) in extracts from HepG2 cells(65K) or LOVO cells(100K). Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH

TGFBR2 antibody
Immunohistochemistry analyzes of AP20273PU-N TGFBR2 antibody in paraffin-embedded Human brain tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH
+1 additional image

TGFBR2 pSer225/250 antibody
Immunohistochemical analysis of paraffin-embedded human brain tissue using TGF β Receptor II (Phospho-Ser225/250) antibody AP55729PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P
0.1 mg / €300.00
  OriGene Technologies GmbH

TGFBR2 pSer225/250 antibody
Immunohistochemical analysis of paraffin-embedded human brain tissue using TGF β Receptor II (Phospho-Ser225/250) antibody AP55729PU-N (left)or the same antibody preincubated with blocking peptide (right). Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €230.00
  OriGene Technologies GmbH

TGFBR2 (Extracell. Dom.) antibody
TGFBR2 Rat IgG2 6G11 Purified Ms WB
0.1 mg / €460.00
  OriGene Technologies GmbH

TGFBR2 antibody
Paraffin-embedded tissue sections of human pituitary were stained with anti-human TGF-beta RII using ABC-HRP, NovaRed (red) substrate and Haematoxylin (blue) counterstain. Goat Aff - Purified Hu E, P, WB
0.1 mg / €430.00
  Neuromics Antibodies
+1 additional image

CRISPR

Catalog No. Species Donor Vector  

Tgfbr2 - mouse gene knockout kit via CRISPR
Tgfbr2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tgfbr2 - mouse gene knockout kit via CRISPR
Tgfbr2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tgfbr2 - mouse gene knockout kit via CRISPR
Tgfbr2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Tgfbr2 - mouse gene knockout kit via CRISPR
Tgfbr2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TGFBR2 (transcript variant 2)
  Recombinant protein of human transforming growth factor, beta receptor II (70/80kDa) (TGFBR2), transcript variant 2  
TGFBR2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

TGFBR2 (transcript variant 2)
  Purified recombinant protein of Human transforming growth factor, beta receptor II (70/80kDa) (TGFBR2), transcript variant 2  
TGFBR2 Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
10 µg / €299.00
  OriGene Technologies, Inc.

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Service
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  • Germany
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  • free call: 0800-227 47 46 (Germany only)
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