THOC7 antibody
Principal name
THOC7 antibody
Alternative names for THOC7 antibody
THO complex subunit 7 homolog, fSAP24, hTREX30, NIF3L1BP1, Functional spliceosome-associated protein 24, Ngg1-interacting factor 3-like protein 1-binding protein 1, NIF3L1-binding protein 1
SwissProt ID
Q6I9Y2 (Human)
Gene ID
80145 (THOC7)
Ncbi ID
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)
Background of THOC7 antibody
THOC7 is a component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mR and not with unspliced pre-mR. It is recruited to spliced mRs by a transcription-independent mechanism. Binds to mR upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mR where it functions in mR export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRs and infectious virus production. The recruitment of the TREX complex to the intronless viral mR occurs via an interaction between KSHV ORF57 protein and ALYREF/THOC4.
General readings
El Bounkari O., et al. (2009) FEBS Lett. 583 (1), 13-18
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA349632 | THOC7 antibody |
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| Rabbit Polyclonal Anti-THOC7 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms | E, P, WB |
0.1 ml /
€335.00
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| OriGene Technologies, Inc. | |||||||
 +1 additional image |
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP309500 | THOC7 |
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| Recombinant protein of human THO complex 7 homolog (Drosophila) (THOC7) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||