Thyrotropin beta chain antibody
Principal name
Thyrotropin beta chain antibody
Alternative names for Thyrotropin beta chain antibody
Thyrotropin subunit beta, Thyroid-stimulating hormone subunit beta, TSH, TSHB, TSH beta
SwissProt ID
O57340 (Chick), P01222 (Human), P01223 (Bovin), P01224 (Pig), P04652 (Rat), P12656 (Mouse), P54828 (Canfa), Q28376 (Horse), Q52R90 (Felca)
Ncbi ID
NP_000540.2, NP_037248.1, NP_000540, 10090, NP_001003290.1, NM_000549, NM_013116
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), ELISA (capture) (E(capture)), ELISA (detection) (E(detection)), Frozen Sections (C), Western blot / Immunoblot (WB), Radioimmunoassay (R), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), EPair for Elisa (EPair)
Background of Thyrotropin beta chain antibody
Thyroid stimulating hormone (TSH), also known as thyrotropin, is secreted from cells in the anterior pituitary called thyrotrophs, finds its receptors on epithelial cells in the thyroid gland, and stimulates that gland to synthesize and release thyroid hormones.
TSH is a glycoprotein hormone composed of two subunits which are non covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones, follicle stimulating hormone and luteinizing hormone, and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity.
TSH has a alpha subunit that is identical to the one in other glycoprotein hormones such as LH, FSH and HCG.
General readings
Kaneshige, M. et al. (2000) Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone. Proc Natl Acad Sci USA. 24: 13209-14.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA327749 | Thyrotropin beta chain antibody |
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| Rabbit Polyclonal TSH Antibody | |||||||
 |
Rabbit | Purified | Hu | P |
1 ml /
€615.00
|
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| OriGene Technologies, Inc. | |||||||
| AM03069PU-N | Thyrotropin beta chain antibody |
||||||
 |
Mouse | IgG2a | TSH-116 | Aff - Purified | Hu | E, R |
0.1 mg /
€190.00
|
| OriGene Technologies GmbH | |||||||
| AM05432PU-N | Thyrotropin beta chain antibody |
||||||
|
Mouse | IgG1 | 154 | Purified | Hu | E |
1 mg /
€720.00
|
| OriGene Technologies GmbH | |||||||
| AM05433PU-N | Thyrotropin beta chain antibody |
||||||
|
Mouse | IgG1 | 155 | Purified | Hu | E |
1 mg /
€720.00
|
| OriGene Technologies GmbH | |||||||
| AM05499PU-N | Thyrotropin beta chain antibody |
||||||
|
Mouse | IgG2a | BC1A3A5 (3A5) | Purified | Hu | E |
1 mg /
€720.00
|
| OriGene Technologies GmbH | |||||||
| AM05501PU-N | Thyrotropin beta chain antibody |
||||||
|
Mouse | IgG1 | 183 | Purified | Hu |
1 mg /
€720.00
|
|
| OriGene Technologies GmbH | |||||||
| AM09312HR-N | Thyrotropin beta chain antibody |
||||||
|
Mouse | IgG1 | TSH-2 | HRP | Hu | E, E(detection) |
0.2 ml /
€480.00
|
| OriGene Technologies GmbH | |||||||
| AM09312PU-N | Thyrotropin beta chain antibody |
||||||
|
Mouse | IgG1 | TSH-2 | Aff - Purified | Hu | E |
0.5 mg /
€450.00
|
| OriGene Technologies GmbH | |||||||
| AM20846PU-N | Thyrotropin beta chain antibody |
||||||
|
Mouse | IgG1 | n.a | Aff - Purified | Hu | E |
1 mg /
€280.00
|
| OriGene Technologies GmbH | |||||||
| AP01099PU-N | Thyrotropin beta chain antibody |
||||||
|
Rabbit | Purified | Rt | C, WB |
50 µl /
€590.00
|
||
| OriGene Technologies GmbH | |||||||
| AP05534PU-N | Thyrotropin beta chain antibody |
||||||
|
Rabbit | IgG | Purified | Can | C, E |
50 µl /
€590.00
|
|
| OriGene Technologies GmbH | |||||||
| AP05535PU-N | Thyrotropin beta chain antibody |
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|
Rabbit | IgG | Purified | Ms | C, P, WB |
50 µl /
€510.00
|
|
| OriGene Technologies GmbH | |||||||
| AP18229PU-N | Thyrotropin beta chain (Center) antibody |
||||||
 |
Rabbit | Hu | WB |
0.4 ml /
€415.00
|
|||
| OriGene Technologies GmbH | |||||||
| 2TS11cc-7G12cc | Thyrotropin beta chain (whole molecule) (in vitro) antibody |
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|
Mouse | IgG1 | 7G12cc | Purified | Hu | E, E(detection) |
1 mg /
€310.00
|
| HyTest Ltd. | |||||||
| 2TS11cc-11E4cc | Thyrotropin beta chain (beta subunit) (in vitro) antibody |
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|
Mouse | IgG1 | 11E4cc | Purified | Hu | E, E(capture) |
1 mg /
€310.00
|
| HyTest Ltd. | |||||||
| 2TS11-TSB1 | Thyrotropin beta chain antibody |
||||||
|
Mouse | IgG1 | TSB1 | Purified | Hu | E, E(capture) |
1 mg /
€310.00
|
| HyTest Ltd. | |||||||
| 2TS11-TSB4 | Thyrotropin beta chain antibody |
||||||
|
Mouse | IgG1 | TSB4 | Purified | Hu | E, E(detection) |
1 mg /
€310.00
|
| HyTest Ltd. | |||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP316914 | Thyrotropin beta chain |
||||
| Purified recombinant protein of Homo sapiens thyroid stimulating hormone, beta (TSHB) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY424650 | TSHB overexpression lysate |
|
|
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. |
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR201419L2V | Lenti ORF particles, Tshb (GFP-tagged ORF) - Rat thyroid stimulating hormone, beta (Tshb), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
