TMEM59L antibody
Principal name
TMEM59L antibody
Alternative names for TMEM59L antibody
Transmembrane protein 59-like, BSMAP, C19orf4, Brain-specific membrane-anchored protein
Ncbi ID
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)
Background of TMEM59L antibody
Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59L is a type I membrane glycoprotein that is expressed in the brain. A related protein, TMEM59, is a Golgi-localized protein that modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP and inhibits APP transport and shedding.
General readings
Elson GC, de Coignac AB, Aubry JP, et al. BSMAP, a novel protein expressed specifically in the brain whose gene is localized on chromosome 19p12. Biochem. Biophys. Res. Commun. 1999; 264:55-62.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA319872 | TMEM59L (C-term) antibody |
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| Rabbit Polyclonal TMEM59L Antibody | |||||||
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Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, ICC/IF, P, WB |
0.1 mg /
€415.00
|
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| OriGene Technologies, Inc. | |||||||
 +2 additional images |
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Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR205011L2V | Lenti ORF particles, Tmem59l (GFP-tagged) - Mouse transmembrane protein 59-like (Tmem59l), 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| MR205011L1V | Lenti ORF particles, Tmem59l (Myc-DDK-tagged) - Mouse transmembrane protein 59-like (Tmem59l), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||