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TMPRSS3 antibody

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Principal name

TMPRSS3 antibody

Alternative names for TMPRSS3 antibody

Transmembrane protease serine 3, ECHOS1, TADG12, TADG-12, Tumor-associated differentially-expressed gene 12 protein

SwissProt ID

P57727 (Human), Q8K1T0 (Mouse)

Gene ID

64699 (TMPRSS3), 140765 (Tmprss3)

Ncbi ID

9606, NP_076927, NP_076927.1, NM_032404, NM_032405, 10090, NM_080727, NM_001163776, NM_024022, NM_032401

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish)

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C)

Background of TMPRSS3 antibody

Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. The TMPRSS3 (also known as ECHOS1) gene, which encodes a transmembrane serine protease, has been found to be responsible for two non-syndromic recessive deafness loci located on human chromosome 21q22.3, DFNB8 and DFNB10.TMPRSS3, a 437 amno acid membrane bound serine protease and a member of the S1 peptidase family. TMPRSS3 contains an amino-terminal signalanchor sequence and a glycosylated extracellular region containing the serine protease domain. Two novel missense mutations of TMPRSS3, W251C and P404L, alter the highly conserved amino acids of the serine protease domain. TMPRSS3 is expressed in many tissues, including fetal cochle,a a subset of pancreatic cancer and various other cancer tissues. TMPRSS3 is also overexpressed in cancer, suggesting that it may be important for processes in metastasis formation and tumor invasion.

General readings

Lee YJ, Park D, Kim SY, Park WJ.
Pathogenic mutations but not polymorphisms in congenital and childhood onset autosomal recessive deafness disrupt the proteolytic activity of TMPRSS3.
J Med Genet. 2003 Aug;40(8):629-31. No abstract available.
PMID: 12920079

PAB7409 - TMPRSS3
TMPRSS3 polyclonal antibody ( Cat # PAB7409 ) ( 0.1 µg/ml ) staining of A-431 cell lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence.
AP20427PU-N - TMPRSS3
Immunohistochemistry analyzes of TMPRSS3 antibody (Cat.-No AP20427PU-N) in paraffin-embedded human breast carcinoma tissue.
AP20427PU-N - TMPRSS3
Western blot analysis of TMPRSS3 antibody (Cat.-No AP20427PU-N) in extracts from HUVEC cells.
C10761-1 - TMPRSS3
Immunofluorescence analysis of HeLa cells, using TMPRSS3 Antibody. The picture on the right is treated with the synthesized peptide.
C10761-1 - TMPRSS3
Western blot analysis of extracts from HuvEc cells, using TMPRSS3 Antibody. The lane on the right is treated with the synthesized peptide.
AP55352PU-N - TMPRSS3
Immunofluorescence of COS cells 293T transfected with pHATMPRSS3.
AP55352PU-N - TMPRSS3
Western Blot using TMPRSS3 antibody Cat.-No AP55352PU-N. 
Lane 1: Total extract from 293T transfected with pHATMPRSS3.
Lane 2: Total extract from 293T transfected with pHA.
AP55353SU-N - TMPRSS3
Immunofluorescence of COS cells transfectecd with pHATMPRSS3
AP55353SU-N - TMPRSS3
Western blot analysis using TMPRSS3 purified antibody: 
Lane 1: Total extract from 293T transfected with pHATMPRSS3.
Lane 2: Total extract from 293T transfected with pHA.
CPA4279-100ul - TMPRSS3
Immunohistochemical analysis of ECHOS1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
CPA4279-100ul - TMPRSS3
Immunofluorescent analysis of ECHOS1 staining in A431 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
CPA4279-100ul - TMPRSS3
Western blot analysis of ECHOS1 expression in A431 (A) whole cell lysates.
TA303305 - TMPRSS3
TA303305 (0.1µg/ml) staining of A431 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
TA315740 - TMPRSS3
Western blot analysis of extracts from HUVEC cells, using TMPRSS3 antibody.The lane on the right is treated with the synthesized peptide.
TA315740 - TMPRSS3
Immunofluorescence analysis of HeLa cells, using TMPRSS3 antibody.The picture on the right is treated with the synthesized peptide.
TA324881 - TMPRSS3
Western blot analysis of TMPRSS3 Antibody (Center) (Cat. #TA324881) in Hela, 293 cell line lysates (35ug/lane). TMPRSS3 (arrow) was detected using the purified Pab.
TA324881 - TMPRSS3
Confocal immunofluorescent analysis of TMPRSS3 Antibody (Center)(Cat#TA324881) with hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
TA338293 - TMPRSS3
Host: Rabbit; Target Name: Tmprss3; Sample Tissue: Mouse Kidney lysates; Antibody Dilution: 1.0 ug/ml
TA344653 - TMPRSS3
WB Suggested Anti-TMPRSS3 Antibody Titration: 5% Milk; Positive Control: Mouse Brain lysate
TA344653 - TMPRSS3
WB Suggested Anti-TMPRSS3 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate
TA344654 - TMPRSS3
WB Suggested Anti-TMPRSS3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: A549 cell lysate
TA351824 - TMPRSS3
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (TMPRSS3 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)

12 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TMPRSS3 antibody
  Goat Polyclonal Antibody against TMPRSS3  
TA303305 (0.1µg/ml) staining of A431 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

TMPRSS3 antibody
  Rabbit polyclonal anti-TMPRSS3 antibody  
Western blot analysis of extracts from HUVEC cells, using TMPRSS3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

TMPRSS3 (Center) antibody
  Rabbit polyclonal TMPRSS3 Antibody (Center)  
Western blot analysis of TMPRSS3 Antibody (Center) (Cat. #TA324881) in Hela, 293 cell line lysates (35ug/lane). TMPRSS3 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €415.00
  OriGene Technologies, Inc.
+1 additional image

TMPRSS3 antibody
  Rabbit Polyclonal Anti-TMPRSS3 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (TMPRSS3 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.

TMPRSS3 antibody
Immunohistochemistry analyzes of TMPRSS3 antibody (Cat.-No AP20427PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH
+1 additional image

TMPRSS3 antibody
Immunofluorescence of COS cells 293T transfected with pHATMPRSS3. Rabbit Aff - Purified Hu C, E, WB
25 µg / €460.00
  OriGene Technologies GmbH
+1 additional image

TMPRSS3 antibody
Immunofluorescence of COS cells transfectecd with pHATMPRSS3 Rabbit Serum Hu C, E, WB
0.2 ml / €430.00
  OriGene Technologies GmbH
+1 additional image

Lysates

Catalog No.    

TMPRSS3 overexpression lysate
TMPRSS3 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tmprss3 (GFP-tagged) - Mouse transmembrane protease, serine 3 (Tmprss3), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, Tmprss3 (GFP-tagged) - Mouse transmembrane protease, serine 3 (Tmprss3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,150.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Tmprss3 (GFP-tagged) - Mouse transmembrane protease, serine 3 (Tmprss3), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, Tmprss3 (GFP-tagged) - Mouse transmembrane protease, serine 3 (Tmprss3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,110.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Tmprss3 (Myc-DDK-tagged) - Mouse transmembrane protease, serine 3 (Tmprss3), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, Tmprss3 (Myc-DDK-tagged) - Mouse transmembrane protease, serine 3 (Tmprss3), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,030.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Tmprss3 (Myc-DDK-tagged) - Mouse transmembrane protease, serine 3 (Tmprss3), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, Tmprss3 (Myc-DDK-tagged) - Mouse transmembrane protease, serine 3 (Tmprss3), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,000.00
  OriGene Technologies, Inc.
 

12 Item(s)

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12 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. Lysate (1)
  2. Mouse Lenti ORF Particle (4)
  3. Primary Antibody (7)
Clonality
  1. Polyclonal (7)
Target
  1. TMPRSS3 (7)
Property
  1. Center (1)
Reactivity
  1. Human (Hu) (7)
  2. Mouse (Ms) (4)
Applications
  1. Western blot / Immunoblot (WB) (6)
  2. Enzyme Immunoassay (E) (4)
  3. Frozen sections (C) (2)
  4. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  5. Paraffin Sections (P) (2)
Presentation
  1. Aff - Purified (3)
  2. Purified (2)
  3. Serum (1)
Host
  1. Rabbit (6)
  2. Goat (1)
Images
  1. 1 image (7)
Images: Applications
  1. Western blot / Immunoblot (WB) (6)
  2. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  3. Immunofluorescence (IF) (2)
  4. IHC (1)
  5. Paraffin Sections (P) (1)
Manufacturer
  1. OriGene Technologies (12)
Service
  • OriGene Technologies GmbH
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  • D-32052 Herford
  • Germany
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  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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