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TNFAIP6 antibody

Principal name

TNFAIP6 antibody

Alternative names for TNFAIP6 antibody

TSG6, TSG-6, Tumor necrosis factor-inducible gene 6 protein, Tumor necrosis factor alpha-induced protein 6, TNF-stimulated gene 6 protein

SwissProt ID

O08859 (Mouse), P98065 (Rabit), P98066 (Human)

Gene ID

7130 (TNFAIP6), 21930 (Tnfaip6)

Ncbi ID

9606, NP_009046.2, NM_007115, NM_009398

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Immunoprecipitation (IP)

Background of TNFAIP6 antibody

TSG6 is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is involved in extracellular matrix stability and cell migration. This protein forms a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhances the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. The expression of this gene can be induced by tumor necrosis factor alpha and interleukin-1. The expression can also be induced by mechanical stimuli in vascular smooth muscle cells, and is correlated with proteoglycan synthesis and aggregation.

Western Blot analysis of TNFAIP6 expression in transfected 293T cell line (H00007130-T01) by TNFAIP6 MaxPab polyclonal antibody.Lane 1: TNFAIP6 transfected lysate(30.58 KDa).Lane 2: Non-transfected lysate.

H00007130-B01

Western blot (WB) analysis of TSG-6 antibody (Cat.-No.: AP01235PU-N) in extracts from Jurkat cells.

AP01235PU-N

Western blot (WB) analysis of TSG-6 antibody (Cat.-No.: AP01235PU-N) in extracts from MCF7 cells.

AP01235PU-N

Western blot analysis of extracts from Jurkat/HeLa/HepG2 cells, using TSG6 Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemical analysis of TSG6 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.

Western blot analysis of TSG6 expression in MCF7 (A); HCT15 (B); HeLa (C) whole cell lysates.

Western blot analysis of extracts from JK cells, HepG2 cells and HuvEc cells, using US28 antibody.The lane on the right is treated with the synthesized peptide.

TA314635

Western blot analysis of TSG6 expression in HeLa cells

TA348042

Primary Antibodies

Catalog No.	Host	Iso.	Pres.	React.	Applications
TA314635	TNFAIP6 antibody
	Rabbit polyclonal anti-US28 antibody
	Rabbit	IgG	Purified	Hu	E, WB	0.1 ml / €335.00
						OriGene Technologies, Inc.
TA348042	TNFAIP6 antibody
	Rabbit Polyclonal Anti-TSG6 Antibody
	Rabbit	IgG	Purified	Hu, Ms	WB	0.1 mg / €335.00
						OriGene Technologies, Inc.
AP01235PU-N	TNFAIP6 antibody
	Rabbit		Aff - Purified	Hu, Ms	ICC/IF, P, WB	0.1 mg / €370.00
						OriGene Technologies GmbH
+1 additional image

Lysates

Catalog No.
LY402092	TNFAIP6 overexpression lysate
		0.1 mg / €295.00
		OriGene Technologies, Inc.

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