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TOMM70A antibody

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Principal name

TOMM70A antibody

Alternative names for TOMM70A antibody

TOM70, KIAA0719, Mitochondrial import receptor subunit TOM70, Mitochondrial precursor proteins import receptor, Translocase of outer membrane 70 kDa subunit

SwissProt ID

O94826 (Human), Q75Q39 (Rat), Q9CZW5 (Mouse)

Gene ID

9868 (TOMM70A), 304017 (Tomm70a)

Ncbi ID

9606, NP_055635, NP_055635.3, NM_014820, AAH03633, NM_212519

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of TOMM70A antibody

Most of mitochondrial proteins are synthesized by cytosolic ribosomes followed by import into mitochondria post-translatiolly with the help of cytosolic chaperones as well as mitochondrial translocators (import components). Translocase of the outer membrane (TOM) complex (TOMM5, TOMM6, TOMM7, TOMM20, TOMM22, TOMM40 and TOMM70) is the proteiceous machinery that contains surface receptors for pre-protein recognition and serve as main entry gateway into mitochondria. Mitochondrial targeting requires different cytosolic factors, in particular the molecular chaperones (Hsc70/Hsp70 and Hsp90) whose activity occur in coordited cycles of ATP hydrolysis/substrate binding and are regulated by a number of co-chaperone proteins including TOM70, a member of TPR (tetratricopeptide repeat) co-chaperone family. TOM70 contains a conserved TPR clamp domain for interaction with Hsc70 and Hsp90, and such interaction is essential for import process initiation. TOMM70 is a single-pass membrane protein localized in mitochondrion outer membrane and is ubiquitously expressed in various tissues where it acts as a receptor that accelerates the import of all mitochondrial precursor proteins. In addition to importing inner membrane carrier proteins, Tom70 is involved in targeting Mcl-1 to outer membrane via an interl EELD sequence.

H00009868-B01P - TOMM70A
Immunofluorescence of purified MaxPab antibody to TOMM70A on HeLa cell. [antibody concentration 10 ug/ml]
H00009868-B01P - TOMM70A
TOMM70A MaxPab polyclonal antibody. Western Blot analysis of TOMM70A expression in human liver.
H00009868-B01P - TOMM70A
Western Blot analysis of TOMM70A expression in transfected 293T cell line by TOMM70A MaxPab polyclonal antibody.Lane 1: TOMM70A transfected lysate(66.88 KDa).Lane 2: Non-transfected lysate.
H00009868-B01P - TOMM70A
TOMM70A MaxPab polyclonal antibody. Western Blot analysis of TOMM70A expression in HepG2.
PAB11995 - TOMM70A
Western blot analysis of TOMM70A in MCF-7 mitochondrial lysate with TOMM70A polyclonal antibody ( Cat# PAB11995 ).
AP17798PU-N - TOMM70A
Western blot analysis of TOMM70A antibody (C-term) (AP17798PU-N) in HL60 cell line lysates (35ug/lane). TOMM70A (arrow) was detected using the purified Pab.
ARP62159_P050 - TOMM70A
Human HeLa; WB Suggested Anti-TOMM70A Antibody. . Titration: 1.0 ug/ml. . Positive Control: Hela Whole Cell. TOMM70A is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells.; TOMM70A antibody - N-terminal region (ARP62159_P050) in Human HeLa cells using Western Blot
TA306693 - TOMM70A
Western blot analysis of TOM70 in 293 cell lysate with TOM70 antibody at 2 ug/ml.
TA306693 - TOMM70A
Immunohistochemistry of TOM70 in mouse brain tissue with TOM70 antibody at 2.5 ug/ml.
TA306693 - TOMM70A
Immunofluorescence of TOM70 in Mouse Brain tissue with TOM70 antibody at 5 ug/mL.
TA306698 - TOMM70A
Western blot analysis of TOM70 in rat brain tissue lysate with TOM70 antibody at (A) 1 and (B) 2 ug/ml.
TA306698 - TOMM70A
Immunohistochemistry of TOM70 in mouse brain tissue with TOM70 antibody at 2.5 ug/ml.
TA306698 - TOMM70A
Immunofluorescence of TOM70 in Mouse Brain cells with TOM70 antibody at 20 ug/mL.
TA336526 - TOMM70A
Western Blot: TOM70 Antibody [TA336526] - Detection of TOM70 in MCF7 mitochondrial lysate
TA336526 - TOMM70A
Immunocytochemistry/Immunofluorescence: TOM70 Antibody [TA336526] - TOM70 antibody was tested in MCF7 cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TOMM70A (N-term) antibody
  Rabbit Polyclonal TOM70 Antibody  
Western blot analysis of TOM70 in 293 cell lysate with TOM70 antibody at 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €415.00
  OriGene Technologies, Inc.
+2 additional images

TOMM70A (Center) antibody
  Rabbit Polyclonal TOM70 Antibody  
Western blot analysis of TOM70 in rat brain tissue lysate with TOM70 antibody at (A) 1 and (B) 2 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €415.00
  OriGene Technologies, Inc.
+2 additional images

TOMM70A antibody
  Rabbit Polyclonal TOM70 Antibody  
Western Blot: TOM70 Antibody [TA336526] - Detection of TOM70 in MCF7 mitochondrial lysate Rabbit Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €415.00
  OriGene Technologies, Inc.
+1 additional image

TOMM70A (C-term) antibody
Western blot analysis of TOMM70A antibody (C-term) (AP17798PU-N) in HL60 cell line lysates (35ug/lane). TOMM70A (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Tomm70a (GFP-tagged ORF) - Rat translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (Tomm70a), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL
Lenti ORF particles, Tomm70a (GFP-tagged ORF) - Rat translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (Tomm70a), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL  
200 µl / €1,340.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Tomm70a (Myc-DDK-tagged ORF) - Rat translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (Tomm70a), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL
Lenti ORF particles, Tomm70a (Myc-DDK-tagged ORF) - Rat translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (Tomm70a), nuclear gene encoding mitochondrial protein, 200 uL, >10^7 TU/mL  
200 µl / €1,200.00
  OriGene Technologies, Inc.
 

6 Item(s)

per page

Available Filters

Product Type
  1. Primary Antibody (4)
  2. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (4)
Target
  1. TOMM70A (4)
Property
  1. C-term (1)
  2. Center (1)
  3. N-term (1)
Reactivity
  1. Human (Hu) (4)
  2. Mouse (Ms) (3)
  3. Rat (Rt) (3)
Applications
  1. Western blot / Immunoblot (WB) (4)
  2. Enzyme Immunoassay (E) (2)
  3. Paraffin Sections (P) (2)
  4. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Presentation
  1. Aff - Purified (2)
  2. Purified (1)
Host
  1. Rabbit (4)
Images
  1. 1 image (4)
  2. 3+ images (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (4)
  2. Immunofluorescence (IF) (3)
  3. IHC (2)
Manufacturer
  1. OriGene Technologies (6)
Service
  • OriGene Technologies GmbH
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  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
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