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TrkA antibody

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Principal name

TrkA antibody

Alternative names for TrkA antibody

NTRK1, TRK, Trk-A, High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor type 1, TRK1-transforming tyrosine kinase protein, p140-TrkA

SwissProt ID

P04629 (Human), P35739 (Rat), Q3UFB7 (Mouse)

Gene ID

4914 (NTRK1), 59109 (Ntrk1), 18211

Ncbi ID

NP_001007793.1, 9606, NP_001007793, NP_067600, NP_067600.1, NP_001028296.1, NM_002529, NM_002529.2, NM_001007792, NP_001012331, NP_002520, NM_021589, NM_001033124

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Enzyme Immunoassay (E), Flow Cytometry (F)

Background of TrkA antibody

Trk A (Neurotrophic tyrosine kinase receptor A) is the high affinity catalytic receptor for the neurotrophin, Nerve Growth Factor (NGF). Higher affinity binding of NGFR can achieved by association with higher molecular mass, low-affinity neurotrophin receptors, namely the tropomyosin receptor kinases, TRKA (NTRK1), TRKB (NTRK2), and TRKC (NTRK3). TRKA, TRKB, and TRKC are specific for or 'preferred by' NGF, NTF4(Neurotrophin-4) and BDNF, and NTF3(Neurotrophin-3), respectively. NTF3 also binds to TRKA and TRKB, but with significantly lower affinity. The absence of TrkA(NGFR) expression was associated with a strong increase in the Sp3 repressor short isoform(s) and a lack of the Sp3 activator long isoform. Sp3 is a bifunctional transcription factor that has been reported to stimulate or repress the transcription of numerous genes. Indo et al. (1996) concluded that defects in TRKA cause CIPA (Congenital insensitivity to pain with anhidrosis ) and that the NGF-TRKA system has a crucial role in the development and function of the nociceptive reception as well as establishment of thermoregulation via sweating in humans. These results also implicate genes encoding other TRK and neurotrophin family members as candidates for developmental defect(s) of the nervous system.

AP00067PU-N - TrkA
Western blot analysis of TrkA expression using Jurkat (Lane 1) and 3T3 (Lane 2) cell lysates.
AP06418PU-N - TrkA
Immunohistochemistry (IHC) analyzes of Trk A antibody (Cat.-No.: AP06418PU-N) in paraffin-embedded human brain tissue.
AP06589PU-N - TrkA
Immunohistochemistry analysis of TrkA Antibody (Cat.-No. AP06589PU-N) in paraffin-embedded Human brain tissue.
AP06589PU-N - TrkA
Western blot analysis of TrkA Antibody (Cat.-No.: AP06589PU-N) in extracts from Jurkat cells.
PAB0629 - TrkA
The NTRK1 (phospho Y791) polyclonal antibody ( Cat # PAB0629 ) is used in Western blot to detect Phospho-NTRK1-Y791 in Ramos cell lysate.
PAB3400 - TrkA
Western blot analysis of NTRK1 polyclonal antibody ( Cat # PAB3400 ) in mouse liver tissue lysates ( 35 µg/lane ) . NTRK1 ( arrow ) was detected using the purified polyclonal antibody.
AP12733PU-N - TrkA
Dot blot analysis of anti-Phospho-TrkA-Y791 Pab (Cat.#AP12733PU-N) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.
AP14434PU-N - TrkA
Western blot analysis of anti-TRKA Antibody (Center) Pab in mouse liver tissue lysates (35ug/lane). TRKA(arrow) was detected using the purified polyclonal antibody.
PAB9064 - TrkA
Western blot analysis of NTRK1 expression in Jurkat ( Lane 1 ) and NIH/3T3 ( Lane 2 ) cell lysates.
AP08798PU-N - TrkA
AP08798PU-N at 2.5 µg/ml, staining TrkA in Adrenal tissue by Immunohistochemistry (Formalin-Fixed Paraffin-Embedded).
PAB14332 - TrkA
Immunohistochemical staining of Tyrosine Kinase Receptor A ( TrkA ) in rat spinal cord ( free floating cryostat section ) using NTRK1 polyclonal antibody ( Cat # PAB14332 ) at a dilution of 1 in 2000. Courtesy of Professor Xin Fu Zhou, The Flinders University of South Australia.
PAB14332 - TrkA
mmunohistochemical staining of Tyrosine Kinase Receptor A ( TrkA ) in rat trigeminal nerve ( free floating cryostat section ) using NTRK1 polyclonal antibody ( Cat # PAB14332 ) at a dilution of 1 in 2000. Courtesy of Professor Xin Fu Zhou, The Flinders University of South Australia.
AP09480PU-N - TrkA
Figure 1. Immunofluorescence staining of methanol-fixed HeLa cells using TrkA pSer791 Antibody (#AP09480PU, Red).
AP09509PU-S - TrkA
Immunofluorescence staining of methanol-fixed HeLa cells using TrkA Antibody
AP18228PU-N - TrkA
Western blot analysis of hTrkA-pY791 (AP18228PU-N) in HepG2 cell line lysates (35ug/lane). TRK (arrow) was detected using the purified Pab.
A0034-1 - TrkA
Immunohistochemistry analysis of paraffin-embedded human brain, using Trk A (Phospho-Tyr791) Antibody. The picture on the right is treated with the synthesized peptide.
A0589-1 - TrkA
Immunofluorescence analysis of NIH-3T3 cells, using Trk A (Phospho-Tyr496) Antibody. The picture on the right is treated with the synthesized peptide.
A8070-1 - TrkA
Immunohistochemistry analysis of paraffin-embedded human brain, using Trk A (Phospho-Tyr701) Antibody. The picture on the right is treated with the synthesized peptide.
A8070-1 - TrkA
Western blot analysis of extracts from mouse brain, using Trk A (Phospho-Tyr701) Antibody. The lane on the right is treated with the synthesized peptide.
A8071-1 - TrkA
Western blot analysis of extracts from Jurkat cells treated with starved 24h, using Trk A (Phospho-Tyr680+Tyr681) Antibody. The lane on the right is treated with the synthesized peptide.
A8194-1 - TrkA
Immunohistochemistry analysis of paraffin-embedded human brain, using Trk A (Phospho-Tyr757) Antibody. The picture on the right is treated with the synthesized peptide.
B0034-1 - TrkA
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Trk A (Ab-791) Antibody. The picture on the right is treated with the synthesized peptide.
B0034-1 - TrkA
Immunofluorescence analysis of HuvEc cells, using Trk A (Ab-791) Antibody. The picture on the right is treated with the synthesized peptide.
B0589-1 - TrkA
Western blot analysis of extracts from Jurkat cells, using Trk A (Ab-496) Antibody. The lane on the right is treated with the synthesized peptide.
B8070-1 - TrkA
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Trk A (Ab-701) Antibody. The picture on the right is treated with the synthesized peptide.
AM06329SU-N - TrkA
Confocal Immunofluorescence analysis of PC-12 cells using TrkA antibody Cat.-No AM06329SU-N (green), showing membrane and cytoplasmic localization. Blue: DRAQ5 fluorescent DNA dye.
AM06329SU-N - TrkA
Western blot analysis using TrkA antibody Cat.-No AM06329SU-N against extracellular domain of human TrkA(aa33-423).
AP55689PU-S - TrkA
Immunohistochemical analysis of paraffin-embedded human brain tissue, using Trk A (phospho-Tyr791) antibody AP55689PU-N (left)or the same antibody preincubated with blocking peptide (right).
AP55776PU-S - TrkA
Immunohistochemical analysis of paraffin-embedded human brain tissue using Trk A (Phospho-Tyr757) antibody AP55776PU-N (left)or the same antibody preincubated with blocking peptide (right).
AP55860PU-S - TrkA
Western blot analysis of extracts from Jurkat cells treated with starved using Phospho-Trk A (Tyr680/Tyr681) antibody AP55860PU-N.The lane on the right is treated with the antigen-specific peptide.
CEK1353 - Human TRK A ELISA Kit
Representative Standard Curve
CEK1640 - Rat TRK A ELISA Kit
Representative Standard Curve
TA806413 - TrkA
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-NTRK1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806413)
TA806413 - TrkA
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NTRK1 (RC213047, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-NTRK1.
TP313091 - TrkA
TP700133 - TrkA
TP700134 - TrkA
TA322998 - TrkA
Predicted cell location: Cytoplasm. Positive control: Human colon and ovarian cancer tissue . Recommended dilution: 1/100-300 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using NTRK1 antibody at dilution 1/90, on the right is treated with the synthetic peptide. (Original magnification:x 200)
TA322998 - TrkA
Predicted cell location: Cytoplasm. Positive control: Human colon and ovarian cancer tissue . Recommended dilution: 1/100-300 The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using NTRK1 antibody at dilution 1/90, on the right is treated with the synthetic peptide. (Original magnification:x200)
TA322999 - TrkA
Predicted cell location: Cytoplasm. Positive control: Human colon and lung cancer tissue . Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using NTRK1 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200)
TA322999 - TrkA
Predicted cell location: Cytoplasm. Positive control: Human colon and lung cancer tissue . Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human lung cancer tissue using NTRK1 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x200)
TA328905 - TrkA
Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain lysates: 1, 2. Anti-TrkA (extracellular) antibody , (1:200). 3, 4. Anti-TrkA (extracellular) antibody, preincubated with the control peptide antigen.
TA328905 - TrkA
Expression of TrkA in rat DRG. Immunohistochemical staining of rat dorsal root ganglia (DRG) frozen sections using Anti-TrkA (extracellular) antibody , (1:100). TrkA (red staining) is expressed in DRG neurons and in satellite microglia (arrows). Hoechst 33342 is used as the counterstain.
TA328905 - TrkA
Expression of TrkA in rat brain hippocampal dentate gyrus. Immunohistochemical staining of immersion-fixed, free floating rat brain frozen sections. A. Brain sections were stained using Anti-TrkA (extracellular) antibody , (1:1000), (green staining). B. The same section was also stained for glial fibrillary acidic protein (GFAP) (red and counterstained blue). C. Overlay of A and B demonstrates co-localization of TrkA and GFAP in dentate gyrus astrocytes.
TA328905 - TrkA
Expression of TrkA in live intact rat PC12 cells. Immunocytochemical staining of live intact rat PC12 cells. A. Cells were stained with Anti-TrkA (extracellular) antibody (1:50), followed by goat anti-rabbit-AlexaFluor-494 secondary antibody (red). B. Cell nuclei were visualized with the membrane-permeable DNA dye Hoechst 33342 (blue staining). C. Live view of the cells.
TA328905 - TrkA
Indirect flow cytometry analysis of live intact Jurkat (human T cell leukemia) cell line: black line: Cells + goat-anti-rabbit-Cy5. Green line: Cells + Anti-TrkA (extracellular) antibody , (1:25) + goat-anti-rabbit-Cy5.
TA326161 - TrkA
Western blot analysis of extracts from mouse brain cells, using Trk A (Phospho-Tyr701) antibody.The lane on the right is treated with the synthesized peptide.
TA326161 - TrkA
Immunohistochemistry analysis of paraffin-embedded human brain tissue using Trk A (Phospho-Tyr701) antibody.The picture on the right is treated with the synthesized peptide.
TA326155 - TrkA
Immunohistochemical analysis of paraffin-embedded human brain tissue, using Trk A (phospho-Tyr791) antibody.The picture on the right is treated with the synthesized peptide.
TA321258 - NTRK1
Predicted band size: 140 kDa . Positive control: Rat and Mouse brain tissue lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1,2: Rat and Mouse brain tissue lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
TA321258 - NTRK1
Predicted cell location: Cell membrane. Positive control: Hela cells. Recommended dilution: 1/ 100-200.The image is immunofluorescence of methanol-fixed Hela cells using NTRK1 (Phospho-Ser791) antibody at dilution 1/100. (Original magnification: ×200)
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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TrkA antibody
  Rabbit polyclonal Anti-TrkA (extracellular)  
Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) brain lysates: 1, 2. Anti-TrkA (extracellular) antibody , (1:200). 3, 4. Anti-TrkA (extracellular) antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €585.00
  OriGene Technologies, Inc.
+4 additional images

Highly validated antibody!

TrkA antibody
  Anti-NTRK1 (Phospho-Ser791) Rabbit Polyclonal Antibody  
Predicted band size: 140 kDa . Positive control: Rat and Mouse brain tissue lysate. Recommended dilution: 1/ 500-1000. (Gel: 8%SDS-PAGE Lane1,2: Rat and Mouse brain tissue lysate Lysates: 30 ug per lane Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu E
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

TrkA antibody
  Anti-NTRK1 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human colon and ovarian cancer tissue . Recommended dilution: 1/100-300 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using NTRK1 antibody at dilution 1/90, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

TrkA antibody
  Anti-NTRK1 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human colon and lung cancer tissue . Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using NTRK1 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

TrkA antibody
  Rabbit polyclonal Trk A (Phospho-Tyr791) antibody  
Immunohistochemical analysis of paraffin-embedded human brain tissue, using Trk A (phospho-Tyr791) antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu P
0.1 ml / €335.00
  OriGene Technologies, Inc.

TrkA antibody
  Rabbit polyclonal Trk A (Phospho-Tyr701) antibody  
Western blot analysis of extracts from mouse brain cells, using Trk A (Phospho-Tyr701) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

TrkA antibody
  NTRK1 mouse monoclonal antibody, clone OTI5B6 (formerly 5B6)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-NTRK1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA806413) Mouse IgG1 OTI5B6 Purified Hu P, WB
0.1 ml / €360.00
  OriGene Technologies, Inc.
+1 additional image

TrueMAB

TrkA antibody
Confocal Immunofluorescence analysis of PC-12 cells using TrkA antibody Cat.-No AM06329SU-N (green), showing membrane and cytoplasmic localization. Blue: DRAQ5 fluorescent DNA dye. Mouse IgG1 6B2 Ascites Hu ICC/IF, WB
0.1 ml / €380.00
  OriGene Technologies GmbH
+1 additional image

TrkA antibody
Western blot analysis of TrkA expression using Jurkat (Lane 1) and 3T3 (Lane 2) cell lysates. Rabbit Purified Hu, Ms, Rt IP, P, WB
0.1 mg / €355.00
  OriGene Technologies GmbH

TrkA antibody
Immunohistochemistry (IHC) analyzes of Trk A antibody (Cat.-No.: AP06418PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu ICC/IF, P
0.1 mg / €370.00
  OriGene Technologies GmbH

TrkA antibody
Immunohistochemistry analysis of TrkA Antibody (Cat.-No. AP06589PU-N) in paraffin-embedded Human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH
+2 additional images

TrkA antibody
AP08798PU-N at 2.5 µg/ml, staining TrkA in Adrenal tissue by Immunohistochemistry (Formalin-Fixed Paraffin-Embedded). Rabbit IgG Aff - Purified Hu, Ms, Rt IP, P, WB
50 µg / €425.00
  OriGene Technologies GmbH

TrkA pSer791 antibody
Figure 1. Immunofluorescence staining of methanol-fixed HeLa cells using TrkA pSer791 Antibody (#AP09480PU, Red). Rabbit Aff - Purified Hu ICC/IF
0.1 mg / €300.00
  OriGene Technologies GmbH

TrkA pSer791 antibody
Figure 1. Immunofluorescence staining of methanol-fixed HeLa cells using TrkA pSer791 Antibody (#AP09480PU, Red). Rabbit Aff - Purified Hu ICC/IF
50 µg / €230.00
  OriGene Technologies GmbH

TrkA antibody
Immunofluorescence staining of methanol-fixed HeLa cells using TrkA Antibody Rabbit Aff - Purified Hu ICC/IF
0.1 mg / €300.00
  OriGene Technologies GmbH

TrkA antibody
Immunofluorescence staining of methanol-fixed HeLa cells using TrkA Antibody Rabbit Aff - Purified Hu ICC/IF
50 µg / €230.00
  OriGene Technologies GmbH

TrkA pTyr791 antibody
Dot blot analysis of anti-Phospho-TrkA-Y791 Pab (Cat.#AP12733PU-N) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

TrkA (Center) antibody
Western blot analysis of anti-TRKA Antibody (Center) Pab in mouse liver tissue lysates (35ug/lane). TRKA(arrow) was detected using the purified polyclonal antibody. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €415.00
  OriGene Technologies GmbH

TrkA antibody
Western blot analysis of hTrkA-pY791 (AP18228PU-N) in HepG2 cell line lysates (35ug/lane). TRK (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

TrkA antibody
TrkA Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €390.00
  OriGene Technologies GmbH

Items 1 to 20 of 38 total

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Product Type
  1. ELISA Kit (2)
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Clonality
  1. Polyclonal (26)
  2. Monoclonal (3)
Target
  1. TrkA (32)
Property
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  4. pSer791 (2)
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  6. pTyr680/681 (2)
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Reactivity
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  2. Mouse (Ms) (14)
  3. Rat (Rt) (11)
Applications
  1. Western blot / Immunoblot (WB) (16)
  2. Paraffin Sections (P) (12)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (8)
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Images
  1. 1 image (29)
  2. 3+ images (2)
  3. 5+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (11)
  2. Paraffin Sections (P) (8)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (5)
  4. IHC (5)
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Species (Protein)
  1. Human (3)
Source
  1. HEK293 cells (2)
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  1. OriGene Technologies (35)
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Service
  • OriGene Technologies GmbH
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  • D-32052 Herford
  • Germany
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  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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