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TTK antibody

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Principal name

TTK antibody

Alternative names for TTK antibody

MPS1, MPS1L1, PYT, Dual specificity protein kinase TTK, Phosphotyrosine picked threonine-protein kinase

SwissProt ID

P33981 (Human), P35761 (Mouse), Q8AYG3 (Danre)

Gene ID

7272 (TTK)

Ncbi ID

9606, 5874, NP_003309, NP_003309.2, NM_003318.3, NM_003318, NM_001166691

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)

Background of TTK antibody

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

H00007272-M01 - TTK
Western Blot analysis of TTK expression in transfected 293T cell line by TTK monoclonal antibody (M01), clone 3G7.Lane 1: TTK transfected lysate(97.1 KDa).Lane 2: Non-transfected lysate.
H00007272-M01 - TTK
TTK monoclonal antibody (M01), clone 3G7 Western Blot analysis of TTK expression in K-562 ( Cat # L009V1 ).
H00007272-M01 - TTK
TTK monoclonal antibody (M01), clone 3G7. Western Blot analysis of TTK expression in HeLa ( Cat # L013V1 ).
H00007272-M01 - TTK
Detection limit for recombinant GST tagged TTK is approximately 0.3ng/ml as a capture antibody.
H00007272-M02 - TTK
TTK monoclonal antibody (M02), clone 4G9 Western Blot analysis of TTK expression in Jurkat ( Cat # L017V1 ).
H00007272-M02 - TTK
Detection limit for recombinant GST tagged TTK is approximately 0.3ng/ml as a capture antibody.
PAB3320 - TTK
Formalin-fixed and paraffin-embedded human cancer tissue reacted with TTK polyclonal antibody ( Cat # PAB3320 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
PAB3320 - TTK
The TTK polyclonal antibody ( Cat # PAB3320 ) is used in Western blot to detect TTK in Jurkat cell lysate.
H00007272-M04 - TTK
TTK monoclonal antibody (M04), clone 2F1 Western Blot analysis of TTK expression in Hela NE ( Cat # L013V3 ).
H00007272-M04 - TTK
Detection limit for recombinant GST tagged TTK is approximately 3ng/ml as a capture antibody.
H00007272-B01 - TTK
Immunofluorescence of purified MaxPab antibody to TTK on HeLa cell. [antibody concentration 10 ug/ml]
H00007272-B01 - TTK
Western Blot analysis of TTK expression in transfected 293T cell line (H00007272-T01) by TTK MaxPab polyclonal antibody.Lane1:TTK transfected lysate(94.27 KDa).Lane2:Non-transfected lysate.
AP15062PU-N - TTK
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
AP15062PU-N - TTK
The anti-TTK Pab is used in Western blot to detect TTK in Jurkat cell lysate.
H00007272-D01 - TTK
Immunoprecipitation of TTK transfected lysate using anti-TTK MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with TTK MaxPab mouse polyclonal antibody (B01) (H00007272-B01).
B8197-1 - TTK
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TTK (Ab-676) Antibody. The picture on the right is treated with the synthesized peptide.
B8197-1 - TTK
Western blot analysis of extracts from HuvEc cells, treated with etoposide 25uM 24H, using TTK (Ab-676) Antibody. The lane on the right is treated with the synthesized peptide.
TP300093 - TTK
TA314651 - TTK
Western blot analysis of extracts from HUVEC cells, treated with etoposide (25uM, 24hours), using TTK (Ab-676) antibody.The lane on the right is treated with the synthesized peptide.
TA314651 - TTK
Western blot analysis of extracts from colo cells (Lane 2), using TTK (Ab-676) Antibody. The lane on the left is treated with synthesized peptide.
TA314651 - TTK
Immunohistochemistry analysis of paraffin-embedded human brain tissue using TTK (Ab-676) antibody.The picture on the right is treated with the synthesized peptide.
TA332526 - TTK
Western blot analysis of extracts of various cell lines, using TTK antibody.
TA347333 - TTK
Western blot analysis on HuvEc cell lysate using TTK Antibody

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TTK antibody
  Rabbit polyclonal TTK (Ab-676) antibody  
Western blot analysis of extracts from HUVEC cells, treated with etoposide (25uM, 24hours), using TTK (Ab-676) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+2 additional images

TTK antibody
  Rabbit anti-TTK Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using TTK antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €335.00
  OriGene Technologies, Inc.

TTK antibody
  Rabbit Polyclonal Anti-TTK Antibody  
Western blot analysis on HuvEc cell lysate using TTK Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

TTK (N-term) antibody
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu P, WB
0.4 ml / €415.00
  OriGene Technologies GmbH
+1 additional image

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

TTK
  Recombinant protein of human TTK protein kinase (TTK)  
TTK Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

Lysates

Catalog No.    

TTK overexpression lysate
TTK overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

6 Item(s)

per page

Available Filters

Product Type
  1. Lysate (1)
  2. Primary Antibody (4)
  3. Protein | Growth Factor (1)
Clonality
  1. Polyclonal (4)
Target
  1. TTK (5)
Property
  1. N-term (1)
Reactivity
  1. Human (Hu) (4)
  2. Mouse (Ms) (3)
  3. Rat (Rt) (1)
Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Paraffin Sections (P) (2)
Presentation
  1. Purified (4)
Host
  1. Rabbit (4)
Images
  1. 1 image (5)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (4)
  2. IHC (1)
  3. Paraffin Sections (P) (1)
Species (Protein)
  1. Human (1)
Source
  1. HEK293 cells (1)
Manufacturer
  1. OriGene Technologies (6)
Service
  • OriGene Technologies GmbH
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  • D-32052 Herford
  • Germany
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  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
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