UBE2M antibody
Principal name
UBE2M antibody
Alternative names for UBE2M antibody
NEDD8-conjugating enzyme Ubc12, Ubiquitin-conjugating enzyme E2 M, NEDD8 protein ligase, NEDD8 carrier protein, UBC12
Ncbi ID
9606, NP_003960.1, NP_003960, NP_663553.1, NM_001168469, NM_145578, NM_003969
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB)
Background of UBE2M antibody
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2M is a member of the E2 ubiquitin-conjugating enzyme family. It is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human UBE2M with an internal ID of P11237
General readings
Gong L., et al. (1999) J. Biol. Chem. 274:12036-12042Huang D.T., et al. (2004) Nat. Struct. Mol. Biol. 11:927-935
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA503770 | UBE2M antibody |
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| UBE2M mouse monoclonal antibody, clone OTI2D9 (formerly 2D9) | |||||||
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Mouse | IgG1 | OTI2D9 | Purified | Can, Hu, Mky, Ms | ICC/IF, WB |
0.1 ml /
€379.00
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| OriGene Technologies, Inc. | |||||||
 +2 additional images |
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Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR201663L2V | Lenti ORF particles, Ube2m (GFP-tagged) - Mouse ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) (Ube2m), transcript variant 2, 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€840.00
|
|
| OriGene Technologies, Inc. | ||
| MR201663L1V | Lenti ORF particles, Ube2m (Myc-DDK-tagged) - Mouse ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) (Ube2m), transcript variant 2, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€740.00
|
|
| OriGene Technologies, Inc. | ||