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UBE4B antibody

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Principal name

UBE4B antibody

Alternative names for UBE4B antibody

Ubiquitin conjugation factor E4 B, UFD2, HDNB1, KIAA0684, Ubiquitin fusion degradation protein 2, Homozygously deleted in neuroblastoma 1

SwissProt ID

O95155 (Human), Q9ES00 (Mouse)

Gene ID

10277 (UBE4B)

Ncbi ID

9606, NP_001099032.1, NM_006048

Available reactivities

Hu (Human), Ms (Mouse), Can (Canine), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of UBE4B antibody

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. The gene that encodes the protein is also the strongest candidate in the neuroblastoma tumor suppressor genes. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human UBE4B with an internal ID of P31336

General readings

Olsen,J.V., (2006) Cell 127 (3), 635-648

H00010277-M01 - UBE4B
UBE4B monoclonal antibody (M01), clone 8F9 Western Blot analysis of UBE4B expression in HeLa NE ( Cat # L013V3 ).
PAB1930 - UBE4B
Formalin-fixed and paraffin-embedded human hepatocellular cancer tissue reacted with UBE4B polyclonal antibody ( Cat # PAB1930 ) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
PAB1930 - UBE4B
The UBE4B polyclonal antibody ( Cat # PAB1930 ) is used in Western blot to detect UBE4B in mouse kidney tissue lysate.
ARP54552_P050 - UBE4B
Human Brain; WB Suggested Anti-UBE4B Antibody Titration: 0.2-1 ug/ml. Positive Control: Human brain; UBE4B antibody - N-terminal region (ARP54552_P050) in Human Brain cells using Western Blot
AP11966PU-N - UBE4B
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
AP11966PU-N - UBE4B
The anti-UBE4B (AP11966PU-N) is used in Western blot to detect UBE4B in mouse kidney tissue lysate.
TA308624 - UBE4B
Sample (30 ug of whole cell lysate). A: Hep G2 . 5% SDS PAGE. TA308624 diluted at 1:10000
TA308624 - UBE4B
Immunohistochemical analysis of paraffin-embedded CA922 xenograft, using UBE4B(TA308624) antibody at 1:500 dilution.
TA308624 - UBE4B
Immunofluorescence analysis of methanol-fixed Hep3B, using UBE4B(TA308624) antibody at 1:500 dilution.
TA335000 - UBE4B
WB Suggested Anti-UBE4B Antibody Titration: 0.2-1 ug/ml; Positive Control: Human brain

2 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UBE4B antibody
  Rabbit polyclonal antibody to UBE4B (ubiquitination factor E4B (UFD2 homolog, yeast))  
Sample (30 ug of whole cell lysate). A: Hep G2 . 5% SDS PAGE. TA308624 diluted at 1:10000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €415.00
  OriGene Technologies, Inc.
+2 additional images

UBE4B (N-term) antibody
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €415.00
  OriGene Technologies GmbH
+1 additional image

2 Item(s)

per page

Available Filters

Product Type
  1. Primary Antibody (2)
Clonality
  1. Polyclonal (2)
Target
  1. UBE4B (2)
Property
  1. N-term (1)
Reactivity
  1. Human (Hu) (2)
  2. Mouse (Ms) (1)
Applications
  1. Paraffin Sections (P) (2)
  2. Western blot / Immunoblot (WB) (2)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Presentation
  1. Aff - Purified (1)
  2. Purified (1)
Host
  1. Rabbit (2)
Images
  1. 1 image (2)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Immunofluorescence (IF) (1)
  3. IHC (1)
  4. Paraffin Sections (P) (1)
Manufacturer
  1. OriGene Technologies (2)
Service
  • OriGene Technologies GmbH
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