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UCMA antibody

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Principal name

UCMA antibody

Alternative names for UCMA antibody

C10orf49, Unique cartilage matrix-associated protein

SwissProt ID

B9TQX4 (Rat), Q14BU0 (Mouse), Q6NWB6 (Danre), Q8WVF2 (Human)

Gene ID

221044 (UCMA), 68527 (Ucma)

Ncbi ID

NP_660357.2, NP_660357, NP_001107030.1, NM_001165932, NM_026754, NM_001113558

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of UCMA antibody

UCMA is a secreted cartilage-specific protein that was discovered in a screen for differentially expressed genes in retinoic acid-treated mouse chondrocytes. It was also identified in a human chondrocyte EST screen for candidate genes of skeletal dysplasias. UCMA expression is thought to parallel that of collagen II with its expression decreasing with maturation chrondrocytes mature. UCMA is processed by a furin-like protease into two fragments, an amino-terminal fragment and a carboxy-terminal fragment (UCMA-C). Application of recombinant UCMA-C to primary osteoblasts, mesenchymal stem cells, and MC3T3-E1 pre-osteoblasts interferes with their osteogenic differentiation, but does not affect expression of chondrocyte-specific genes or chondrocyte proliferation, suggesting that UCMA may be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells. At least two isoforms of UCMA are known to exist.

AP23876PU-N - UCMA
Human Lung, Chondrocytes: Formalin-Fixed, Paraffin-Embedded (FFPE)
AP23876PU-N - UCMA
Western blot analysis of UCMA in SW1353 cell lysate with UCMA antibody at (A) 2.5 and (B) 5 µg/ml.
TA306793 - UCMA
Western blot analysis of UCMA in SW1353 cell lysate with UCMA antibody at (A) 2.5 and (B) 5 µg/ml.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UCMA antibody
  Rabbit Polyclonal UCMA Antibody  
Western blot analysis of UCMA in SW1353 cell lysate with UCMA antibody at (A) 2.5 and (B) 5 µg/ml. Rabbit IgG Aff - Purified Hu, Ms E, WB
0.1 mg / €415.00
  OriGene Technologies, Inc.

UCMA (C-term) antibody
Human Lung, Chondrocytes: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms E, P, WB
50 µg / €425.00
  OriGene Technologies GmbH
+1 additional image

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ucma (GFP-tagged) - Mouse upper zone of growth plate and cartilage matrix associated (Ucma), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, Ucma (GFP-tagged) - Mouse upper zone of growth plate and cartilage matrix associated (Ucma), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Ucma (GFP-tagged) - Mouse upper zone of growth plate and cartilage matrix associated (Ucma), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, Ucma (GFP-tagged) - Mouse upper zone of growth plate and cartilage matrix associated (Ucma), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Ucma (GFP-tagged) - Mouse upper zone of growth plate and cartilage matrix associated (Ucma), transcript variant 3, 200 uL, >10^7 TU/mL
Lenti ORF particles, Ucma (GFP-tagged) - Mouse upper zone of growth plate and cartilage matrix associated (Ucma), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Ucma (Myc-DDK-tagged) - Mouse upper zone of growth plate and cartilage matrix associated (Ucma), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, Ucma (Myc-DDK-tagged) - Mouse upper zone of growth plate and cartilage matrix associated (Ucma), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Ucma (Myc-DDK-tagged) - Mouse upper zone of growth plate and cartilage matrix associated (Ucma), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, Ucma (Myc-DDK-tagged) - Mouse upper zone of growth plate and cartilage matrix associated (Ucma), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Ucma (Myc-DDK-tagged) - Mouse upper zone of growth plate and cartilage matrix associated (Ucma), transcript variant 3, 200 uL, >10^7 TU/mL
Lenti ORF particles, Ucma (Myc-DDK-tagged) - Mouse upper zone of growth plate and cartilage matrix associated (Ucma), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

8 Item(s)

per page

Available Filters

Product Type
  1. Mouse Lenti ORF Particle (6)
  2. Primary Antibody (2)
Clonality
  1. Polyclonal (2)
Target
  1. UCMA (2)
Property
  1. C-term (1)
Reactivity
  1. Human (Hu) (2)
  2. Mouse (Ms) (2)
Applications
  1. Enzyme Immunoassay (E) (2)
  2. Western blot / Immunoblot (WB) (2)
  3. Paraffin Sections (P) (1)
Presentation
  1. Aff - Purified (1)
  2. Purified (1)
Host
  1. Rabbit (2)
Images
  1. 1 image (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Paraffin Sections (P) (1)
Manufacturer
  1. OriGene Technologies (8)
Service
  • OriGene Technologies GmbH
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  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
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