WISP1 antibody
Principal name
WISP1 antibody
Alternative names for WISP1 antibody
CCN4, WNT1-inducible-signaling pathway protein 1, CCN family member 4, Wnt-1-induced secreted protein
Ncbi ID
NP_001191798.1, 9606, O95388, NP_061353.1, NM_080838, NM_003882, NP_003873, NM_018865, NM_001204869, NM_031716
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)
Background of WISP1 antibody
This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83% identical to the mouse protein at the amino acid level. Multiple alternatively spliced transcript variants have been identified.
General readings
Major MB, Camp ND, Berndt JD, Yi X, Goldenberg SJ, Hubbert C, Biechele TL, Gingras AC, Zheng N, Maccoss MJ, Angers S, Moon RT.
Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.
Science. 2007 May 18;316(5827):1043-6.
PMID: 17510365
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA302635 | WISP1 (C-term) antibody |
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| Goat Polyclonal Antibody against WISP1 | |||||||
 |
Goat | Aff - Purified | Hu, Ms, Rt | WB |
0.1 mg /
€360.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA351929 | WISP1 antibody |
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| Rabbit Polyclonal Anti-WISP1 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA590295 | WISP1 antibody |
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| Rabbit Polyclonal WISP1 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu |
50 µg /
€409.00
|
||
| OriGene Technologies, Inc. | |||||||
| AP13229PU-N | WISP1 (Center) antibody |
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 |
Rabbit | Ig | Purified | Hu | P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
 +1 additional image |
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP310402 | WISP1 (transcript variant 1) |
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| Recombinant protein of human WNT1 inducible signaling pathway protein 1 (WISP1), transcript variant 1 | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
| TP723479 | WISP1 (transcript variant 1) |
||||
| Purified recombinant protein of Human WNT1 inducible signaling pathway protein 1 (WISP1), transcript variant 1. | |||||
 |
Human | > 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
20 µg /
€230.00
|
|
| OriGene Technologies, Inc. | |||||
ELISA Kits
| Catalog No. | ||
|---|---|---|
| EA100709 | Human WISP1/CCN4 ELISA Kit |
|
|
1 kit /
€500.00
|
|
| OriGene Technologies, Inc. | ||
| EA100702 | Mouse WISP1/CCN4 ELISA Kit |
|
|
1 kit /
€500.00
|
|
| OriGene Technologies, Inc. |
Lysates
| Catalog No. | ||
|---|---|---|
| LY403320 | WISP1 overexpression lysate |
|
|
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. | ||
| LY418374 | WISP1 overexpression lysate |
|
|
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. |
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR205645L2V | Lenti ORF particles, Wisp1 (GFP-tagged) - Mouse WNT1 inducible signaling pathway protein 1 (Wisp1), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| MR205645L1V | Lenti ORF particles, Wisp1 (Myc-DDK-tagged) - Mouse WNT1 inducible signaling pathway protein 1 (Wisp1), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR209420L2V | Lenti ORF particles, Wisp1 (GFP-tagged ORF) - Rat WNT1 inducible signaling pathway protein 1 (Wisp1), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| RR209420L1V | Lenti ORF particles, Wisp1 (Myc-DDK-tagged ORF) - Rat WNT1 inducible signaling pathway protein 1 (Wisp1), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||