YDJ1 / MAS5 antibody
Principal name
YDJ1 / MAS5 antibody
Alternative names for YDJ1 / MAS5 antibody
Yeast dnaJ protein 1, Mitochondrial protein import protein MAS5
SwissProt ID
P25491 (Yeast)
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB)
Background of YDJ1 / MAS5 antibody
Human Hsp40/DnaJ proteins comprise a large protein family, members of which feature the J domain (named after the bacterial DnaJ protein) (1). The J-domain spans the first 75 N-terminal amino acids and is separated from the C-terminal by a glycine/phenylalanine-rich domain (2). There are two main types of Hsp40; type 1 DNAJ proteins including HDJ2 and yeast YdjI; type II includes yeast Sis1 and human Hdj1. Whereas type I possesses a zinc finger domain which helps in the function of protein folding. (3, 4), type II does not.
Members of the Hsp40/DnaJ family play diverse roles in many cellular processes, such as folding, translocation, degradation and assembly of multi-protein complexes. Hsp40 stimulates the ATPase activity of Hsp70 which in turn causes conformational changes of the unfolded proteins (5, 6). The Hsp40-Hsp70-unfolded protein complex further binds to co-chaperones Hip, Hop and HSP90 which leads to protein folding, or components of protein degradation machinery CHIP and BAG-1 (7).
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA309370 | YDJ1 / MAS5 antibody |
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| Mouse Monoclonal anti-DNAJA2 Antibody | |||||||
 |
Mouse | IgG1 | 2A7.H6 | Purified | Ye | E, IP, WB |
0.1 mg /
€405.00
|
| OriGene Technologies, Inc. | |||||||
