YEATS4 antibody
Principal name
YEATS4 antibody
Alternative names for YEATS4 antibody
GAS41, NuBI1, NuBI-1, YEATS domain-containing protein 4, Glioma-amplified sequence 41, NuMA-binding protein 1
Ncbi ID
NP_006521, NP_006521.1, 9606, NM_006530, NP_080846.1, NM_026570
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of YEATS4 antibody
Gene amplification is associated with tumor stage and progression in human gliomas. Several amplified loci are identified and comprise multiple genes. The glioma amplified sequence 41 (GAS41) is an evolutionarily conserved eukaryotic protein found in diverse species. GAS41 is related to the AF-9 and ENL proteins, which are putative transcription factors in some acute leukemias,and interacts with a component of the nuclear matrix, NuMA, in interphase cells. GAS41 has a dotted staining pattern in interphase nuclei and a uniform distribution in mitotic cells. GAS41 is ubiquitously expressed, with the highest levels of expression in human brain. In neuroblastoma, GAS41 is located in the nucleoli, but not in the nucleoplasm. GAS41 also binds to the MLL fusion partner AF-10, which is involved in two distinct chromosomal translocations associated with hematologic malignancy. In addition, GAS41 interacts with INI1 (integrase interactor 1), which is a human homolog of the yeast Snf5 protein, a component of the SWI/SNF complex. The GAS41 gene maps to human chromosome 12q13-q15.
General readings
Harborth J. et al. (2000) J. Biol. Chem. 275:31979-31985.Debernardi S. et al. (2002) Blood. 99: 275-81.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA314716 | YEATS4 antibody |
||||||
| Rabbit polyclonal anti-GAS41 antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms | E, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA347600 | YEATS4 antibody |
||||||
| Rabbit Polyclonal Anti-GAS41 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms | WB |
0.1 mg /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| AP06652PU-N | YEATS4 antibody |
||||||
 |
Rabbit | Aff - Purified | Hu, Ms | WB |
0.1 mg /
€370.00
|
||
| OriGene Technologies GmbH | |||||||
| AP11696PU-N | YEATS4 (N-term) antibody |
||||||
 |
Rabbit | Ig | Purified | Hu, Ms | WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
| AP54594PU-N | YEATS4 antibody |
||||||
 |
Rabbit | Ig | Aff - Purified | Hu | WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP301526 | YEATS4 |
||||
| Purified recombinant protein of Homo sapiens YEATS domain containing 4 (YEATS4) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY401956 | YEATS4 overexpression lysate |
|
 |
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. |
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR202676L2V | Lenti ORF particles, Yeats4 (GFP-tagged) - Mouse YEATS domain containing 4 (Yeats4), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| MR202676L1V | Lenti ORF particles, Yeats4 (Myc-DDK-tagged) - Mouse YEATS domain containing 4 (Yeats4), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||