Zonulin antibody
Principal name
Zonulin antibody
Available reactivities
Available hosts
Available applications
Frozen Sections (C), Enzyme Immunoassay (E), Paraffin Sections (P)
Background of Zonulin antibody
Zonulin is a protein that participates in tight junctions between cells of the wall of the digestive tract. Initially discovered in 2000 as the target of zonula occludens toxin, secreted by cholera pathogen Vibrio cholerae, it has been implicated in the pathogenesis of coeliac disease and diabetes mellitus type 1. It is being studied as a target for vaccine adjuvants. ALBA Therapeutics is developing a zonulin receptor antagonist, AT-1001, that is currently in phase 2 clinical trials.
Immunofluorescence staining of Zonulin in Cryosection of astrocytoma WHO III. Zonulin antibody Cat.-No AP02266SU marks the beginning degradation of the blood-brain barrier with Zonulin (green) localized at the blood vessels (GSI agglutinin, red). Skardelly M et al.(2009) Transl Oncol 2(3): 117-120.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AP02266SU-N | Zonulin (GGVLVQPG) antibody |
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Rabbit | Serum | Hu | C, E, P |
0.1 ml /
€500.00
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| OriGene Technologies GmbH | |||||||
| AP02266SU-S | Zonulin (GGVLVQPG) antibody |
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|
Rabbit | Serum | Hu | C, E, P |
20 µl /
€170.00
|
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| OriGene Technologies GmbH | |||||||