TA306384 TSLP (C-term) antibody

Rabbit Polyclonal TSLP Antibody

See related secondary antibodies

Search for all "TSLP"

0.1 mg / €415.00
Please visit the country specific website of OriGene Technologies or contact your local Distributor to buy this product.

Quick Overview

Rabbit anti Human TSLP

TA306384

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  • TA306384

Product Description for TSLP

Rabbit anti Human TSLP.
Properties: (C-term)
Presentation: Aff - Purified
Product is tested for Enzyme Immunoassay, Paraffin Sections, Western blot / Immunoblot.

Properties for TSLP

Product Category Primary Antibodies
Target Category
Quantity 0.1 mg
Synonyms Thymic stroma-derived lymphopoietin, Thymic stromal lymphopoietin
Presentation Aff - Purified
Reactivity Hu
Applications E, P, WB
Clonality Polyclonal
Host Rabbit
Isotype IgG
Shipping to Europe, USA/Canada
PDF datasheet View Datasheet
Manufacturer OriGene Technologies, Inc.

Datasheet Extract

Immunogen
Swiss Prot Num:
Q969D9
Immunogen:
TSLP antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human TSLP.
GeneID:
85480
Property C-term
Add. information Blocking peptide available: AP30963CP-N
Application ELISA.
Western blot: 1 – 2 μg/ml.
Immunohistochemistry on paraffin sections.
Background Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. TSLP is a four-helix-bundle cytokine that is expressed mainly by barrier epithelial cells and is a potent activator of several cell types such as myeloid dendritic cells. TSLP is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Amino acid sequence analysis has shown poor homology between human and mouse TSLP although they exhibit similar biological functions and are expressed in similar tissues. Despite its predicted molecular weight, TSLP often migrates at a higher molecular weight in SDS-PAGE. At least two differentially spliced isoforms of TSLP are known to exist.
General Readings
  1. Ziegler SF, Liu YJ. Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nat Immunol. 2006 Jul;7(7):709-14. PubMed PMID: 16785889.
  2. Sims JE, Williams DE, Morrissey PJ, Garka K, Foxworthe D, Price V, et al. Molecular cloning and biological characterization of a novel murine lymphoid growth factor. J Exp Med. 2000 Sep 4;192(5):671-80. PubMed PMID: 10974033. (Free PMC Article available, 6 images available)
  3. Levin SD, Koelling RM, Friend SL, Isaksen DE, Ziegler SF, Perlmutter RM, et al. Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism. J Immunol. 1999 Jan 15;162(2):677-83. PubMed PMID: 9916685.
  4. Quentmeier H, Drexler HG, Fleckenstein D, Zaborski M, Armstrong A, Sims JE, et al. Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation. Leukemia. 2001 Aug;15(8):1286-92. PubMed PMID: 11480573.
Storage Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Peptide affinity chromatography
Buffer System:
PBS containing 0.02% sodium azide
State:
Liquid Ig fraction
Aff - Purified
Species Reactivity
Species reactivity (tested):
Human
Specificity
Specificity:
This antibody detects TSLP at C-term.

Accessory Products

Proteins and/or Positive Controls

Proteins for TSLP (16 products)

Catalog No. Species Pres. Purity   Source  

TSLP (transcript variant 1)

TSLP Human > 95 %
Preparation: .
Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
10 µg / €230.00
  OriGene Technologies, Inc.

TSLP (transcript variant 1)

TSLP Human > 98 %
Preparation: .
Purity Detail: >98%, as determined by Coomassie stained SDS-PAGE.
E. coli
10 µg / €255.00
  OriGene Technologies, Inc.

TSLP

TSLP Human > 98 % pure by SDS-PAGE and HPLC analyses E. coli
  OriGene Technologies GmbH

TSLP

TSLP Human > 98 % pure by SDS-PAGE and HPLC analyses E. coli
  OriGene Technologies GmbH

TSLP (29-159, His-tag)

TSLP Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €820.00
  OriGene Technologies GmbH

TSLP (29-159, His-tag)

TSLP Human Purified > 85 % by SDS - PAGE E. coli
20 µg / €320.00
  OriGene Technologies GmbH

TSLP

TSLP Human
  Abnova Taiwan Corp.

TSLP

TSLP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

TSLP

TSLP Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
  Abnova Taiwan Corp.

TSLP

TSLP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

TSLP

TSLP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
  Abnova Taiwan Corp.

TSLP

TSLP Human
  Abnova Taiwan Corp.

TSLP

TSLP Human Purified
  Novus Biologicals Inc.

TSLP

TSLP Human Purified
  Novus Biologicals Inc.

TSLP

TSLP Human Purified
  Novus Biologicals Inc.

TSLP

TSLP Human Purified
  Novus Biologicals Inc.

Positive controls for TSLP (2 products)

Catalog No. Species Pres. Purity   Source  

TSLP overexpression lysate

TSLP overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.

TSLP overexpression lysate

TSLP overexpression lysate
0.1 mg / €295.00
  OriGene Technologies, Inc.
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