discontinued

AP42370PU-N ASIC3 / ACCN3 antibody

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Rabbit anti Bovine, Canine, Human, Mouse, Rat ASIC3 / ACCN3

AP42370PU-N

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  • AP42370PU-N

Product Description for ASIC3 / ACCN3

Rabbit anti Bovine, Canine, Human, Mouse, Rat ASIC3 / ACCN3.
Presentation: Aff - Purified
Product is tested for Paraffin Sections, Western blot / Immunoblot.

Properties for ASIC3 / ACCN3

Product Category Primary Antibodies
Quantity 0.1 mg
Synonyms Acid-sensing ion channel 3, Amiloride-sensitive cation channel 3, Neuronal amiloride-sensitive cation channel 3, SLNAC1, TNAC1, Testis sodium channel 1
Presentation Aff - Purified
Reactivity Bov, Can, Hu, Ms, Rt
Applications P, WB
Clonality Polyclonal
Host Rabbit
Shipping to Worldwide
PDF datasheet View Datasheet
Manufacturer OriGene Technologies GmbH
Material safety datasheet MSDS for Polyclonal Antibodies (de)

Datasheet Extract

Immunogen
Swiss Prot Num:
Q9UHC3
Immunogen:
Synthetic peptide directed directed towards the N terminal of human ACCN3
GeneID:
9311
Application Western blotting (1 - 3 µg/ml)
Immunohistochemistry on paraffin embedded sections (4-8 µg/ml)
Background ACCN3 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. ACCN3 encodes a member that is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and ACCN1 has been observed as proton-gated channels sensitive to gadolinium.
General Readings
  1. Babinski K, Lê KT, Séguéla P. Molecular cloning and regional distribution of a human proton receptor subunit with biphasic functional properties. J Neurochem. 1999 Jan;72(1):51-7. PubMed PMID: 9886053.
  2. de Weille JR, Bassilana F, Lazdunski M, Waldmann R. Identification, functional expression and chromosomal localisation of a sustained human proton-gated cation channel. FEBS Lett. 1998 Aug 21;433(3):257-60. PubMed PMID: 9744806.
Storage Store undiluted at 2-8°C for one month or (in aliquots) at -20°C to -80°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Format
Purification:
Purified using Protein A affinity column
State:
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Aff - Purified
Species Reactivity
Species reactivity (expected):
Mouse, Rat, Rabbit, Dog, Bovine, Guinea Pig, Horse
Species reactivity (tested):
Human
Gene ID 9311

Accessory Products

Proteins and/or Positive Controls

Positive controls for ASIC3 / ACCN3 (1 products)

Catalog No. Species Pres. Purity   Source  

Amiloride-sensitive cation channel 3 Lysate

Western Blot: Amiloride-sensitive cation channel 3 Lysate [NBL1-07232] - Western Blot experiments.  Left-Control; Right -Over-expression Lysate for ACCN3. Protein
  Novus Biologicals Inc.
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