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ACOX1 antibody

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Principal name

ACOX1 antibody

Alternative names for ACOX1 antibody

AOX, Palmitoyl-CoA oxidase, Straight-chain acyl-CoA oxidase, Peroxisomal acyl-coenzyme A oxidase 1

SwissProt ID

P07872 (Rat), Q15067 (Human), Q3SZP5 (Bovin), Q9R0H0 (Mouse), Q9Z1N0 (Cavpo)

Gene ID

51 (ACOX1), 11430 (Acox1), 50681

Ncbi ID

9606, NP_001171968.1, NM_001185039, 10090, NM_015729, NM_017340, NM_004035, NM_007292

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Eq (Equine), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P)

Background of ACOX1 antibody

ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. 
Function: Catalyzes the desaturation of acyl-CoAs to 2-trans- enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy- palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl- CoA.
Cellular Location: Peroxisome. 
Tissue Location: Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart.

PAB4367 - ACOX1
Western blot analysis of ACOX1 polyclonal antibody ( Cat # PAB4367 ) in mouse liver lysate . Data is kindly provided by Hye Won Kang and Dr . McGrane at the Univ . of Connecticut ( Storrs, CT ) .
PAB4368 - ACOX1
Western blot analysis of ACOX1 ( arrow ) using rabbit ACOX1 polyclonal antibody ( Cat # PAB4368 ) . 293 cell lysates ( 2 µg/lane ) either nontransfected ( Lane 1 ) or transiently transfected with the ACOX1 gene ( Lane 2 ) ( Origene Technologies ) .
H00000051-B01P - ACOX1
Immunofluorescence of purified MaxPab antibody to ACOX1 on HeLa cell. [antibody concentration 10 ug/ml]
H00000051-B01P - ACOX1
Western Blot analysis of ACOX1 expression in transfected 293T cell line (H00000051-T01) by ACOX1 MaxPab polyclonal antibody.Lane 1: ACOX1 transfected lysate(72.6 KDa).Lane 2: Non-transfected lysate.
AP12247PU-N - ACOX1
Western blot analysis of anti-ACOX1 Pab (Cat.#AP12247PU-N) in mouse liver lysate. Data is kindly provided by Hye Won Kang and Dr. McGrane at the Univ. of Connecticut (Storrs, CT).
AP12248PU-N - ACOX1
(LEFT) Western blot analysis of ACOX1 (arrow) using rabbit polyclonal ACOX1 Antibody (C-term) (Cat#AP12248PU-N). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ACOX1 gene (Lane 2) (Origene Technologies). (RIGHT) Western blot analysis of ACOX1 (arrow) using rabbit polyclonal ACOX1 Antibody (C-term) (Cat#AP12248PU-N). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ACOX1 gene (Lane 2) (Origene Technologies).
H00000051-D01P - ACOX1
Western Blot analysis of ACOX1 expression in transfected 293T cell line (H00000051-T01) by ACOX1 MaxPab polyclonal antibody.Lane 1: ACOX1 transfected lysate(74.70 KDa).Lane 2: Non-transfected lysate.
AM33416PU-N - ACOX1
Immunohistochemistry analysis in Formalin Fixed and Paraffin Embedded human colon carcinomastained with ACOX1 Monoclonal Antibody Cat.-No AM33416PU-N (Clone 153CT43.1.1) followed by peroxidase conjugation of the secondary antibody and DAB staining.
AM33416PU-N - ACOX1
Confocal immunofluorescent analysis of ACOX1 Monoclonal Antibody Cat.-No AM33416PU-N (Clone 153CT43.1.1) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).
AM33416PU-N - ACOX1
Western blot analysis in K562 cell line lysates using ACOX1 Monoclonal Antibody Cat.-No AM33416PU-N (Clone 153CT43.1.1) (15ug/lane). This demonstrates the ACOX1 antibody detected the ACOX1 protein (arrow). (1 µg/ml)1:390
TA324047 - ACOX1
Predicted band size: 74 kDa . Positive control: Mouse stomach, liver and kidney tissue lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lane1: Mouse stomach tissue lysate Lane2: Mouse liver tissue lysate Lane3: Mouse kidney tissue lysate Lysates: 40 ug per lane Primary antibody: 1/350 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
TA324047 - ACOX1
Predicted cell location: Cytoplasm. Positive control: Human cervical cancer tissue. Recommended dilution: 1/15-50 The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using ACOX1 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification: x 200)
TA324048 - ACOX1
Predicted cell location: Cytoplasm. Positive control: Human cervical and thyroid cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human cervical cancer tissue using ACOX1 antibody at dilution 1/40, on the right is treated with the fusion protein. (Original magnification:x 200)
TA324048 - ACOX1
Predicted cell location: Cytoplasm. Positive control: Human cervical and thyroid cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using ACOX1 antibody at dilution 1/40, on the right is treated with the fusion protein. (Original magnification:x200)
TA335908 - ACOX1
Host: Rabbit; Target Name: Paox; Sample Tissue: Rat Pancreas lysates; Antibody Dilution: 1.0 ug/ml

2 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ACOX1 antibody
  Anti-ACOX1 rabbit polyclonal antibody  
Predicted band size: 74 kDa . Positive control: Mouse stomach, liver and kidney tissue lysate. Recommended dilution: 1/200-1000. (Gel: 8%SDS-PAGE Lane1: Mouse stomach tissue lysate Lane2: Mouse liver tissue lysate Lane3: Mouse kidney tissue lysate Lysates: 40 ug per lane Primary antibody: 1/350 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

ACOX1 antibody
  Anti-ACOX1 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human cervical and thyroid cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human cervical cancer tissue using ACOX1 antibody at dilution 1/40, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

2 Item(s)

per page

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Product Type
  1. Primary Antibody (2)
Clonality
  1. Polyclonal (2)
Target
  1. ACOX1 (2)
Reactivity
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  2. Mouse (Ms) (2)
  3. Rat (Rt) (2)
Presentation
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  1. Rabbit (2)
Images
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Images: Applications
  1. IHC (2)
  2. Western blot / Immunoblot (WB) (1)
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