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CD70 antibody

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Principal name

CD70 antibody

Alternative names for CD70 antibody

CD27 ligand, CD27L, CD27LG, TNFSF7, Tumor necrosis factor ligand superfamily member 7

SwissProt ID

O55237 (Mouse), P32970 (Human), Q3ZDR4 (Pig)

Gene ID

21948 (Cd70), 970 (CD70)

Ncbi ID

9606, NP_001243, NP_035747.1, NM_001252, NP_001243.1, AAH00725.1, NM_011617

Available reactivities

Hu (Human), Ms (Mouse), Mky (Monkey), Gorilla, Rt (Rat)

Available hosts

Mouse, Rat, Rabbit

Available applications

Frozen Sections (C), Flow Cytometry (F), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of CD70 antibody

CD27 Ligand, a type II transmembrane protein, is a member of the TNF superfamily. It is expressed on activated T and B lymphocytes as well as NK cells. CD27L and its receptor (CD27) regulate the immune response by promoting T-cell expansion and differentiation, as well as NK enhancement. CD27 signaling can act as a co-stimulatory effector to sustain the survival of CD8+ T cells, primarily by inducing increased expression of the IL-2 gene. Full length human CD27L is a 193 amino acid protein, consisting of a 17 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 155 amino acid extracellular domain. Human soluble CD27L corresponds to the 155 amino acid extracellular domain of the full length CD27L protein. The provided human sCD27L protein contains the extracellular domain plus an N-terminal His-Tag.

General readings

Welten SP., et al. (2013) J. Virol. 87:6851-6865.Polak ME., et al. (2012) J. Invest. Dermatol. 132:1636-1644.

AM05527PU-T - CD70
Immunofluorescence staining of a human tonsil cryosection with Mouse anti Human CD70 antibody, clone Bu69 (Cat.-No AM05527PU), red in A and Mouse anti Human CD21 antibody, clone LB21, green in B. C is the merged image with nuclei counterstained blue using DAPI. Low power.
AM05527PU-T - CD70
Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD70 antibody, clone Bu69 (Cat.-No AM05527PU) followed by the Histar setection system. High power.
AM05527PU-T - CD70
Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD70 antibody, clone Bu69 (Cat.-No AM05527PU) followed by the Histar setection system. Medium power.

AM05527PU-T - CD70
Immunoperoxidase staining of a human tonsil cryosection with Mouse anti Human CD70 antibody, clone Bu69 (Cat.-No AM05527PU) followed by the Histar setection system. Low power
H00000970-B01P - CD70
Western Blot analysis of CD70 expression in transfected 293T cell line (H00000970-T01) by CD70 MaxPab polyclonal antibody.Lane 1: TNFSF7 transfected lysate(21.23 KDa).Lane 2: Non-transfected lysate.
ARP61309_P050 - CD70
Human ACHN; WB Suggested Anti-CD70 Antibody. . Titration: 1.0 ug/ml. . Positive Control: ACHN Whole Cell. CD70 is supported by BioGPS gene expression data to be expressed in ACHN.; CD70 antibody - N-terminal region (ARP61309_P050) in Human ACHN cells using Western Blot
AR51818PU-N - CD70
CPA1188-100ul - CD70
Western blot analysis of CD70 expression in Jurkat (A); NCIH460 (B) whole cell lysates.
TP300410 - CD70
TA308292 - CD70
Sample (30 ug of whole cell lysate). A: JurKat. 12% SDS PAGE. CD27L (CD70) antibody. TA308292 diluted at 1:1000.
TA311855 - CD70
Western blot analysis of extracts from HuvEC, K562, HepG2, Jurkat, HeLa and COLO205 cells, using CD70 antibody.The lane on the right is treated with the synthesized peptide.
TA318843 - CD70
Anti-CD70 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA318843 - CD70
Anti-CD70 antibody IHC of human tonsil.. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA318844 - CD70
Anti-CD70 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA318844 - CD70
Anti-CD70 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA318845 - CD70
Anti-CD70 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA318845 - CD70
Anti-CD70 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA320290 - CD70
Surface staining of LPS and Anti-Mouse/Rat CD40 Functional Grade Purified stimulated mouse splenocytes with Anti-Mouse CD70 PE . Autofluorescence is shown via open histogram. Total viable cells were used for analysis.
TA321314 - CD70
Predicted band size: 21 kDa . Positive control: NCI-H460 cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
TA327233 - CD70
Western blot analysis of extracts of various cell lines, using CD70 antibody.
TA327233 - CD70
Immunofluorescence analysis of U2OS cell using CD70 antibody. Blue: DAPI for nuclear staining.
TA347946 - CD70
Western blot analysis of CD70 expression in COLO205 cells
AR52063PU-N - CD70
TA351933 - CD70
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (CD70 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
TA351933 - CD70
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using (CD70 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CD70 antibody
  CD70 Rabbit Polyclonal (Internal) Antibody  
Anti-CD70 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Hu, Mky
50 µg / €425.00
  OriGene Technologies, Inc.
+1 additional image

CD70 antibody
  CD70 Rabbit Polyclonal (Internal) Antibody  
Anti-CD70 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Gorilla, Hu, Mky
50 µg / €425.00
  OriGene Technologies, Inc.
+1 additional image

CD70 antibody
  CD70 Rabbit Polyclonal (N-Terminus) Antibody  
Anti-CD70 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit IgG Purified Hu
50 µg / €425.00
  OriGene Technologies, Inc.
+1 additional image

CD70 antibody
  Rabbit Polyclonal Anti-CD70 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using (CD70 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200) Rabbit IgG Purified Hu E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

4 Item(s)

per page

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  1. Primary Antibody (4)
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  1. Enzyme Immunoassay (E) (1)
  2. Paraffin Sections (P) (1)
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