ERCC1 antibody
Principal name
ERCC1 antibody
Alternative names for ERCC1 antibody
DNA excision repair protein ERCC-1, COFS4, UV20
Ncbi ID
NP_001974.1, 9606, NP_001974, NP_001159521, NP_973730.1, NM_202001, NP_973730, NM_007948, NM_001983, NM_001166049
Available reactivities
Available hosts
Available applications
Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of ERCC1 antibody
The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of D lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the D lesion. The heterodimeric endonuclease is also involved in recombitiol D repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009].
General readings
Zhang N, Liu X, Li L, Legerski R. Double-strand breaks induce homologous recombinational repair of interstrand crosslinks via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway. DNA Repair (Amst). 2007 Jul 30. PMID: 17669695


Lane1: MCF-7 whole cell lysate
Lane2: Mouse liver tissue lysate
Lane3: Rat kidney tissue lysate




























































































































































- Quick-Filters:
- Highly Validated (1)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA332586 | ERCC1 antibody |
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| Rabbit anti-ERCC1 Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
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| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
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| TA303306 | ERCC1 (N-term) antibody |
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| Goat Polyclonal Antibody against ERCC1 | |||||||
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Goat | Aff - Purified | Hu | E, WB |
0.1 mg /
€360.00
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| OriGene Technologies, Inc. | |||||||
| TA326228 | ERCC1 antibody |
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| Rabbit polyclonal ERCC1 antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms | WB |
0.1 ml /
€335.00
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|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA347375 | ERCC1 antibody |
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| Rabbit Polyclonal Anti-ERCC1 Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms | WB |
0.1 mg /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| AP06106PU-N | ERCC1 antibody |
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Rabbit | Aff - Purified | Hu, Ms | P, WB |
0.1 mg /
€370.00
|
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| OriGene Technologies GmbH | |||||||
+1 additional image |
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| AP23054PU-N | ERCC1 (172-184) antibody |
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Goat | Aff - Purified | Bov, Bt, Can, Elephant, Hu, Mky, Ms, Platypus, Rt | E, P |
50 µg /
€425.00
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| OriGene Technologies GmbH | |||||||
| AP54924PU-N | ERCC1 antibody |
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Rabbit | Purified | Hu | C, E, WB |
0.1 mg /
€450.00
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| OriGene Technologies GmbH | |||||||














































+3 additional images




