ERCC1 antibody

Principal name

ERCC1 antibody

Alternative names for ERCC1 antibody

DNA excision repair protein ERCC-1, COFS4, UV20

SwissProt ID

P07903 (Mouse), P07992 (Human), Q1LZ75 (Bovin)

Gene ID

2067 (ERCC1), 13870 (Ercc1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bt (Bat), Bov (Bovine), Can (Canine), Eq (Equine), Hst (Hamster), Mky (Monkey), Op (Opossum), Por (Porcine), Prim (Primate), Xen (Xenopus), Ze (Zebrafish), Bear

Available hosts

Mouse, Rabbit, Goat

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of ERCC1 antibody

The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of D lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the D lesion. The heterodimeric endonuclease is also involved in recombitiol D repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009].

General readings

Zhang N, Liu X, Li L, Legerski R. Double-strand breaks induce homologous recombinational repair of interstrand crosslinks via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway. DNA Repair (Amst). 2007 Jul 30. PMID: 17669695

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ERCC1 antibody

  Rabbit anti-ERCC1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using ERCC1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €335.00
  OriGene Technologies, Inc.

ERCC1 (N-term) antibody

  Goat Polyclonal Antibody against ERCC1  
TA303306 (0.3µg/ml) staining of A431 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

ERCC1 antibody

  Rabbit polyclonal ERCC1 antibody  
Western blot analysis of extracts from NIH/3T3 cells, using ERCC1 antibody (#TA326228).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

ERCC1 antibody

  Rabbit Polyclonal Anti-ERCC1 Antibody  
Western blot analysis on NIH-3T3 cell lysate using ERCC1 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

ERCC1 antibody

Immunohistochemistry (IHC) analysis of ERCC1 antibody (Cat.-No.: AP06106PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH

ERCC1 (172-184) antibody

AP23054PU-N ERCC1 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Tonsil. Goat Aff - Purified Bov, Bt, Can, Elephant, Hu, Mky, Ms, Platypus, Rt E, P
50 µg / €425.00
  OriGene Technologies GmbH

ERCC1 antibody

ERCC1 Rabbit Purified Hu C, E, WB
0.1 mg / €450.00
  OriGene Technologies GmbH

7 Item(s)

per page
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