Galectin-3 antibody
Principal name
Galectin-3 antibody
Alternative names for Galectin-3 antibody
Mac-2, Lgals3, GAL3, GALBP, CBP35, L-31, Galactose-specific lectin 3, IgE-binding protein, 35 kDa lectin, Carbohydrate-binding protein 35, Laminin-binding protein, Lectin L-29, L-34 galactoside-binding lectin
Ncbi ID
NP_002297.2, NP_002297, 9606, NP_034835.1, 10090, AAH01120, NM_001177388
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Functional assay (FN), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Luminex (LMNX)
Background of Galectin-3 antibody
Galectin-3 is a member of the galectin family. The protein is composed of three domains: a small amino-terminal domain, a carboxyl-terminal carbohydrate recognition domain (CRD) and amino-terminal domain containing repeating elements. Galectin-3 is normally distributed in epithelia of many organs and various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. The expression is also affected by neoplastic transformation: up-regulated in certain types of lymphomas and thyroid carcinoma, while down-regulated in other types of malignancies, such as colon, breast, ovarian and uterine carcinomas.
Galectin-3 has been shown to function through both intracellular and extracellular actions. Related to its intracellular functions, galectin-3 has been identified as a component of heterogeneous nuclear ribonuclear protein (hnRNP), a factor in pre-mRNA splicing, and has been found to control cell cycle and prevent T cell apoptosis. On the other hand, this protein has also been demonstrated to function as extracellular molecule in activating various types of cells, including monocytes/macrophages, mast cells, neutrophils and lymphocytes. Galectin-3 has been shown to mediate cell-cell and cell-extracellular matrix interactions.
General readings
1. Ma F et al. The requirement of CD8+ T cells to initiate and augment acute cardiac inflammatory response to high blood pressure. J Immunol 192:3365-73 (2014). IHC-P,ICC/IF ; Mouse .PubMed: 24600037
2. Lee YJ et al. Spatial and temporal expression, and statin responsiveness of galectin-1 and galectin-3 in murine atherosclerosis. Korean Circ J 43:223-30 (2013). IHC-FoFr ; Mouse .PubMed: 23682281
3. Reticker-Flynn NE et al. A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis. Nat Commun 3:1122 (2012).WB .PubMed: 23047680
4. Doe JA et al. Transgenic overexpression of the a7 integrin reduces muscle pathology and improves viability in the dy(W) mouse model of merosin-deficient congenital muscular dystrophy type 1A. J Cell Sci 124:2287-97 (2011). WB, IHC-Fr ; Mouse .PubMed: 21652631
5. Checinska A et al. Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells. J Proteomics 72:575-85 (2009).PubMed: 19118655





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- Quick-Filters:
- Cited (2)
- Highly Validated (15)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| CL049B | Galectin-3 antibody |
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Rat | IgG2a | M3/38 | Biotin | Ms | C, E, F, P |
0.1 mg /
€340.00
|
| OriGene Technologies GmbH | |||||||
Published recently! |
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| CL049P | Galectin-3 antibody |
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Rat | IgG2a | M3/38 | Purified | Ms | C, E, F, ICC/IF, P, WB |
0.1 mg /
€300.00
|
| OriGene Technologies GmbH | |||||||
Published recently! |
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| UM500104 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody,clone UMAB157 | |||||||
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Mouse | IgG1 | UMAB157 | Purified | Hu | P, WB |
0.1 ml /
€468.00
|
| OriGene Technologies, Inc. | |||||||
+20 additional images |
Highly validated antibody! |
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| UM570104 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody,clone UMAB157 | |||||||
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Mouse | IgG1 | UMAB157 | Purified | Hu | P, WB |
30 µl /
€180.00
|
| OriGene Technologies, Inc. | |||||||
+20 additional images |
Highly validated antibody! |
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| UM800081 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody,clone UMAB189 | |||||||
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Mouse | IgG1 | UMAB189 | Purified | Hu | P |
0.1 ml /
€468.00
|
| OriGene Technologies, Inc. | |||||||
+4 additional images |
Highly validated antibody! |
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| UM870081 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody,clone UMAB189 | |||||||
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Mouse | IgG1 | UMAB189 | Purified | Hu | P |
30 µl /
€180.00
|
| OriGene Technologies, Inc. | |||||||
+4 additional images |
Highly validated antibody! |
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| TA506397 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody, clone OTI1A2 (formerly 1A2) | |||||||
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Mouse | IgG1 | OTI1A2 | Purified | Hu | ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+6 additional images |
Highly validated antibody! |
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| TA506398 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody, clone OTI1A4 (formerly 1A4) | |||||||
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Mouse | IgG1 | OTI1A4 | Purified | Hu | ICC/IF, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
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| TA506399 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody, clone OTI1G8 (formerly 1G8) | |||||||
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Mouse | IgG1 | OTI1G8 | Purified | Can, Hu, Ms, Rt | ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+8 additional images |
Highly validated antibody! |
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| TA506400 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody, clone OTI1A3 (formerly 1A3) | |||||||
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Mouse | IgG1 | OTI1A3 | Purified | Hu | ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+5 additional images |
Highly validated antibody! |
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| TA506401 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody, clone OTI1A1 (formerly 1A1) | |||||||
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Mouse | IgG1 | OTI1A1 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+11 additional images |
Highly validated antibody! |
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| TA801621 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody, clone OTI1C7 (formerly 1C7) | |||||||
| Mouse | IgG | OTI1C7 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
|
| OriGene Technologies, Inc. | |||||||
+22 additional images |
Highly validated antibody! |
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| TA804567 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody, clone OTI2F1 (formerly 2F1) | |||||||
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Mouse | IgG2b | OTI2F1 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+21 additional images |
Highly validated antibody! |
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| TA804612 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody, clone OTI7G9 (formerly 7G9) | |||||||
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Mouse | IgG1 | OTI7G9 | Purified | Hu | P |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+13 additional images |
Highly validated antibody! |
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| TA804656 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody, clone OTI9C7 (formerly 9C7) | |||||||
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Mouse | IgG1 | OTI9C7 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+4 additional images |
Highly validated antibody! |
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| TA804694 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody, clone OTI6E1 (formerly 6E1) | |||||||
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Mouse | IgG2a | OTI6E1 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+19 additional images |
Highly validated antibody! |
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| TA804697 | Galectin-3 antibody |
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| LGALS3 mouse monoclonal antibody, clone OTI15E4 (formerly 15E4) | |||||||
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Mouse | IgG1 | OTI15E4 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+16 additional images |
Highly validated antibody! |
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| AP23674PU-N | Galectin-3 antibody |
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Goat | Aff - Purified | Ms | E, WB |
0.1 mg /
€380.00
|
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| OriGene Technologies GmbH | |||||||
OriGene recommends this product for Western blotting. |
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| TA311983 | Galectin-3 antibody |
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| Rabbit polyclonal Galectin 3 antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA320412 | Galectin-3 antibody |
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| Rat Anti-Human/Mouse Galectin-3 Purified (50 ug) | |||||||
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Rat | eBioM3/38 (M3/38) | Purified | Ms | E, F, IP, P, WB |
50 µg /
€155.00
|
|
| OriGene Technologies, Inc. | |||||||





















































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