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Human Lambda Light Chain antibody

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Principal name

Human Lambda Light Chain antibody

Available reactivities

Hu (Human), Rb (Rabbit), Mky (Monkey)

Available hosts

Mouse, Rabbit, Goat

Available applications

Frozen Sections (C), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (capture) (E(capture)), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Flow Cytometry (F), Immunoprecipitation (IP), Immunodiffusion (ID), Dot blot (Dot)

Background of Human Lambda Light Chain antibody

All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins). This antibody stains only lambda light chain containing cells in human lymphoid tissues.

General readings

Reynolds, W. M. et al (1992) A simple technique for the determination of kappa and lambda immunoglobulin light chain expression by B cells in whole blood: J. Imm. Meth. 151:123-129.

GTX73553 - Human Lambda Light Chain
IHC Image using GTX73553 - Detection of Lambda Light Chain by IHC in Human Tonsil
AM12139PU-N - Human Lambda Light Chain
B lymphocytes (CD19+) in a dot-plot Lambda PE vs. Kappa FITC. Kappa light chain detected by A8B5 antibody and lambda light chain by 4C2 antibody, CD19 by LT19 antibody.
AM12139FC-N - Human Lambda Light Chain
B lymphocytes (CD19+) in a dot-plot Lambda PE vs. Kappa FITC. Kappa light chain detected by A8B5 antibody and lambda light chain by 4C2 antibody, CD19 by LT19 antibody.
AM12139RP-N - Human Lambda Light Chain
B lymphocytes (CD19+) in a dot-plot Lambda PE vs. Kappa FITC. Kappa light chain detected by A8B5 antibody and lambda light chain by 4C2 antibody, CD19 by LT19 antibody.
AM12139AC-N - Human Lambda Light Chain
B lymphocytes (CD19+) in a dot-plot Lambda PE vs. Kappa FITC. Kappa light chain detected by A8B5 antibody and lambda light chain by 4C2 antibody, CD19 by LT19 antibody.
DB 039-0.5 - Human Lambda Light Chain
Formalin-Fixed and Paraffin Embedded Human tonsil tissue stained with anti-Human Lambda Light Chain antibody (DB 039). Kindly performed and provided by Katarina Poliakova, MD and Lubomir Straka, MD, Ph. D. from Clinical Pathology Presov, Ltd., Presov, Slovakia.
DB 039-1 - Human Lambda Light Chain
Formalin-Fixed and Paraffin Embedded Human tonsil tissue stained with anti-Human Lambda Light Chain antibody (DB 039). Kindly performed and provided by Katarina Poliakova, MD and Lubomir Straka, MD, Ph. D. from Clinical Pathology Presov, Ltd., Presov, Slovakia.
DB 039-0.2 - Human Lambda Light Chain
Formalin-Fixed and Paraffin Embedded Human tonsil tissue stained with anti-Human Lambda Light Chain antibody (DB 039). Kindly performed and provided by Katarina Poliakova, MD and Lubomir Straka, MD, Ph. D. from Clinical Pathology Presov, Ltd., Presov, Slovakia.
DB 039-0.1 - Human Lambda Light Chain
Formalin-Fixed and Paraffin Embedded Human tonsil tissue stained with anti-Human Lambda Light Chain antibody (DB 039). Kindly performed and provided by Katarina Poliakova, MD and Lubomir Straka, MD, Ph. D. from Clinical Pathology Presov, Ltd., Presov, Slovakia.
AM10107SU-N - Human Lambda Light Chain
Formalin-Fixed, Paraffin-Embedded Human tonsil stained with Lambda Light Chain antibody Cat.-No. AM10107SU-N using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining of plasma cells.
AM39034FC-N - Human Lambda Light Chain
Representative DataThe reactivity of anti-lambda-FITC antibody in combination with anti-CD19-PE is illustrated by flow cytometry analysis of normal human peripheral blood B cells.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Human Lambda Light Chain antibody
B lymphocytes (CD19+) in a dot-plot Lambda PE vs. Kappa FITC. Kappa light chain detected by A8B5 antibody and lambda light chain by 4C2 antibody, CD19 by LT19 antibody. Mouse IgG1 4C2 APC Hu F
100 Tests / €290.00
  OriGene Technologies GmbH

Human Lambda Light Chain antibody
B lymphocytes (CD19+) in a dot-plot Lambda PE vs. Kappa FITC. Kappa light chain detected by A8B5 antibody and lambda light chain by 4C2 antibody, CD19 by LT19 antibody. Mouse IgG1 4C2 FITC Hu F
100 Tests / €260.00
  OriGene Technologies GmbH

Human Lambda Light Chain antibody
B lymphocytes (CD19+) in a dot-plot Lambda PE vs. Kappa FITC. Kappa light chain detected by A8B5 antibody and lambda light chain by 4C2 antibody, CD19 by LT19 antibody. Mouse IgG1 4C2 Aff - Purified Hu C, E, F, P
0.1 mg / €230.00
  OriGene Technologies GmbH

Human Lambda Light Chain antibody
B lymphocytes (CD19+) in a dot-plot Lambda PE vs. Kappa FITC. Kappa light chain detected by A8B5 antibody and lambda light chain by 4C2 antibody, CD19 by LT19 antibody. Mouse IgG1 4C2 PE Hu F
100 Tests / €290.00
  OriGene Technologies GmbH

Human Lambda Light Chain antibody
Surface staining of lambda light chains in human peripheral blood with anti-lambda light chains (1-155-2) PE. Mouse IgG1 1-155-2 FITC Hu F
100 Tests / €260.00
  OriGene Technologies GmbH

Human Lambda Light Chain antibody
Surface staining of lambda light chains in human peripheral blood with anti-lambda light chains (1-155-2) PE. Mouse IgG1 1-155-2 Purified Hu F
0.1 mg / €230.00
  OriGene Technologies GmbH

Human Lambda Light Chain antibody
Surface staining of lambda light chains in human peripheral blood with anti-lambda light chains (1-155-2) PE. Mouse IgG1 1-155-2 PE Hu F
100 Tests / €290.00
  OriGene Technologies GmbH

Human Lambda Light Chain antibody
Human Lambda Light Chain Mouse IgG1 48 Supernatant Hu C, E, P
1 ml / €260.00
  OriGene Technologies GmbH

Human Lambda Light Chain (free and bound) antibody
Representative Data The reactivity of anti-lambda-FITC antibody in combination with anti-CD19-PE is illustrated by flow cytometry analysis of normal human peripheral blood B cells. Mouse IgG1 NaM79-8E6 FITC Hu F
100 Tests / €430.00
  OriGene Technologies GmbH

Human Lambda Light Chain (free and bound) antibody
Representative Data The reactivity of anti-lambda-FITC antibody in combination with anti-CD19-PE is illustrated by flow cytometry analysis of normal human peripheral blood B cells. Mouse IgG1 NaM79-8E6 PE Hu F
100 Tests / €510.00
  OriGene Technologies GmbH

Human Lambda Light Chain antibody
Human Lambda Light Chain Mouse IgG2a 2G9 Purified Hu C, E, P
0.5 mg / €560.00
  OriGene Technologies GmbH

Human Lambda Light Chain antibody
Human Lambda Light Chain Mouse IgG1 N10/2 Supernatant Hu C, P
1 ml / €450.00
  OriGene Technologies GmbH

Human Lambda Light Chain antibody
Human Lambda Light Chain Mouse IgG1 N10/2 Supernatant Hu C, P
0.5 ml / €300.00
  OriGene Technologies GmbH

Human Lambda Light Chain antibody
Human Lambda Light Chain Rabbit Purified Hu C, P
1 ml / €330.00
  OriGene Technologies GmbH

Human Lambda Light Chain antibody
Human Lambda Light Chain Rabbit Purified Hu C, P
0.5 ml / €270.00
  OriGene Technologies GmbH

Human Lambda Light Chain (F(ab)2 Fragment) antibody
Human Lambda Light Chain Goat AP
0.5 mg / €340.00
  OriGene Technologies GmbH

Human Lambda Light Chain (F(ab)2 Fragment) antibody
Human Lambda Light Chain Goat Biotin
1 mg / €320.00
  OriGene Technologies GmbH

Human Lambda Light Chain (F(ab)2 Fragment) antibody
Human Lambda Light Chain Goat FITC
1 mg / €320.00
  OriGene Technologies GmbH

Human Lambda Light Chain (F(ab)2 Fragment) antibody
Human Lambda Light Chain Goat HRP
1 mg / €340.00
  OriGene Technologies GmbH

Human Lambda Light Chain (F(ab)2 Fragment) antibody
Human Lambda Light Chain Goat Aff - Purified
1 mg / €285.00
  OriGene Technologies GmbH

Items 1 to 20 of 26 total

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26 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. Primary Antibody (26)
Clonality
  1. Monoclonal (17)
  2. Polyclonal (9)
Target
  1. Human Lambda Light Chain (26)
Property
  1. F(ab)2 Fragment (7)
  2. free and bound (2)
Reactivity
  1. Human (Hu) (19)
Applications
  1. Flow cytometry (F) (12)
  2. Frozen sections (C) (7)
  3. Paraffin Sections (P) (7)
  4. Enzyme Immunoassay (E) (5)
  5. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Presentation
  1. Purified (6)
  2. FITC (5)
  3. PE (4)
  4. Supernatant (3)
  5. Aff - Purified (2)
  6. AP (1)
  7. APC (1)
  8. Biotin (1)
  9. HRP (1)
  10. TRITC (1)
  11. Texas Red (1)
Host
  1. Mouse (17)
  2. Goat (7)
  3. Rabbit (2)
Images
  1. 1 image (9)
Images: Applications
  1. Flow cytometry (F) (9)
Manufacturer
  1. OriGene Technologies (26)
Service
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