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IRF2 antibody

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Principal name

IRF2 antibody

Alternative names for IRF2 antibody

Interferon regulatory factor 2, IRF-2

SwissProt ID

P14316 (Human), P23906 (Mouse), Q98925 (Chick)

Gene ID

3660 (IRF2), 16363 (Irf2)

Ncbi ID

9606, NP_002190, NP_002190.2, NM_002199, NM_008391

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair)

Background of IRF2 antibody

Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3gamma p48 (the 48 kDa component of the ISGF-3 complex) and IFN consensus sequence-binding protein (ICSBP).

General readings

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)
Lace, M.J., et al. Virology 399(2):270-279(2010)
Masumi, A., et al. Biochem. Biophys. Res. Commun. 391(4):1623-1628(2010)
Daley, D., et al. Hum. Genet. 125(4):445-459(2009)
Dhar, D., et al. PLoS ONE 4 (9), E7049 (2009)

H00003660-M02 - IRF2
Immunoperoxidase of monoclonal antibody to IRF2 on formalin-fixed paraffin-embedded human leiomyosarcoma. [antibody concentration 3 ug/ml]
H00003660-M02 - IRF2
Immunofluorescence of monoclonal antibody to IRF2 on HeLa cell. [antibody concentration 10 ug/ml]
H00003660-M02 - IRF2
IRF2 monoclonal antibody (M02), clone 3B5 Western Blot analysis of IRF2 expression in Hela NE ( Cat # L013V3 ).
H00003660-M02 - IRF2
Western Blot analysis of IRF2 expression in transfected 293T cell line by IRF2 monoclonal antibody (M02), clone 3B5.Lane 1: IRF2 transfected lysate(39.4 KDa).Lane 2: Non-transfected lysate.
H00003660-M02 - IRF2
Detection limit for recombinant GST tagged IRF2 is approximately 0.1ng/ml as a capture antibody.
P100943_T100 - IRF2
Human Jurkat; WB Suggested Anti-IRF2 Antibody Titration: 5.0ug/ml. Positive Control: Jurkat cell lysate; IRF2 antibody - N-terminal region (P100943_T100) in Human Jurkat cells using Western Blot
H00003660-M01 - IRF2
Immunofluorescence of monoclonal antibody to IRF2 on HeLa cell. [antibody concentration 10 ug/ml]
H00003660-M01 - IRF2
IRF2 monoclonal antibody (M01), clone 3D6 Western Blot analysis of IRF2 expression in Hela NE ( Cat # L013V3 ).
H00003660-M01 - IRF2
Detection limit for recombinant GST tagged IRF2 is approximately 0.03ng/ml as a capture antibody.
H00003660-M04 - IRF2
Immunofluorescence of monoclonal antibody to IRF2 on HeLa cell. [antibody concentration 10 ug/ml]
H00003660-M04 - IRF2
IRF2 monoclonal antibody (M04), clone 7C2 Western Blot analysis of IRF2 expression in Hela NE ( Cat # L013V3 ).
H00003660-M04 - IRF2
Detection limit for recombinant GST tagged IRF2 is approximately 0.03ng/ml as a capture antibody.
AP06668PU-N - IRF2
Immunohistochemistry (IHC) analyzes of IRF-2 antibody (Cat.-No.: AP06668PU-N) in paraffin-embedded human colon carcinoma tissue.
AP06668PU-N - IRF2
Western blot (WB) analysis of IRF-2 antibody (Cat.-No.: AP06668PU-N) in extracts from Jurkat cells.
PAB6225 - IRF2
IRF2 polyclonal antibody ( Cat # PAB6225 ) staining ( 2 µg/ml ) of Jurkat lysate ( RIPA buffer, 30 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
H00003660-D01P - IRF2
Western Blot analysis of IRF2 expression in transfected 293T cell line (H00003660-T01) by IRF2 MaxPab polyclonal antibody.Lane 1: IRF2 transfected lysate(39.40 KDa).Lane 2: Non-transfected lysate.
AR09056PU-L - IRF2
AR09056PU-L - IRF2
IRF-2: 15% SDS-PAGE (3 µg)
C10366-1 - IRF2
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using IRF2 Antibody. The picture on the right is treated with the synthesized peptide.
C10366-1 - IRF2
Western blot analysis of extracts from Jurkat/COLO205 cells, using IRF2 Antibody. The lane on the right is treated with the synthesized peptide.
AP52235PU-N - IRF2
Western blot analysis of IRF2 Antibody (Center) Cat.-No AP52235PU-N in mouse bladder tissue lysates (35ug/lane). This demonstrates the IRF2 antibody detected the IRF2 protein (arrow).
AP52235PU-N - IRF2
Western blot analysis of IRF2 Antibody (Center) Cat.-No AP52235PU-N in Jurkat cell line lysates (35ug/lane). This demonstrates the IRF2 antibody detected the IRF2 protein (arrow).
TP302102 - IRF2
TP710148 - IRF2
TA302517 - IRF2
TA302517 staining (2µg/ml) of Jurkat lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
TA311964 - IRF2
Western blot analysis of extracts from Jurkat cells and COLO205 cells, using IRF2 antibody.The lane on the right is treated with the synthesized peptide.
TA311964 - IRF2
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using IRF2 antibody.The picture on the right is treated with the synthesized peptide.
TA330031 - IRF2
WB Suggested Anti-IRF2 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate
TA330146 - IRF2
WB Suggested Anti-IRF2 Antibody Titration: 5.0ug/ml; Positive Control: Jurkat cell lysate
TA352216 - IRF2
Total cell lysate from Jurkat cells (lane 1), Ramos cells (lane 2), and mouse splenocytes (lane 3) were resolved by electrophoresis, transferred to nitrocellulose, and probed with purified monoclonal anti-IRF2 (clone 13B2A38) antibody. Proteins were visualized using an anti-mouse-IgG secondary conjugated to HRP and chemiluminescence detection.
TA352216 - IRF2
Jurkat cells were stained with purified anti-IRF2 (13B2A38) antibody, followed by staining with DyLight™ 488 conjugated goat anti-mouse IgG (green) antibody. Nuclei were stained with DAPI (blue).

9 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

IRF2 (C-term) antibody
  Goat Polyclonal Antibody against IRF2  
TA302517 staining (2µg/ml) of Jurkat lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

IRF2 antibody
  Rabbit polyclonal anti-IRF2 antibody  
Western blot analysis of extracts from Jurkat cells and COLO205 cells, using IRF2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

IRF2 antibody
Immunohistochemistry (IHC) analyzes of IRF-2 antibody (Cat.-No.: AP06668PU-N) in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH
+1 additional image

IRF2 (Center) antibody
Western blot analysis of IRF2 Antibody (Center) Cat.-No AP52235PU-N in mouse bladder tissue lysates (35ug/lane). This demonstrates the IRF2 antibody detected the IRF2 protein (arrow). Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €415.00
  OriGene Technologies GmbH
+1 additional image

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

IRF2
  Recombinant protein of human interferon regulatory factor 2 (IRF2)  
IRF2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

IRF2 (full length, C-term DDK tag)
  Recombinant protein of human interferon regulatory factor 2 (IRF2), full length, with C-terminal DDK tag, expressed in sf9, 20ug  
IRF2 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 SF9 cells
20 µg / €411.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

IRF2 overexpression lysate
IRF2 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Irf2 (GFP-tagged) - Mouse interferon regulatory factor 2 (Irf2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Irf2 (GFP-tagged) - Mouse interferon regulatory factor 2 (Irf2), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Irf2 (Myc-DDK-tagged) - Mouse interferon regulatory factor 2 (Irf2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Irf2 (Myc-DDK-tagged) - Mouse interferon regulatory factor 2 (Irf2), 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

9 Item(s)

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Available Filters

Product Type
  1. Lysate (1)
  2. Mouse Lenti ORF Particle (2)
  3. Primary Antibody (4)
  4. Protein | Growth Factor (2)
Clonality
  1. Polyclonal (4)
Target
  1. IRF2 (6)
Property
  1. C-term (1)
  2. Center (1)
Reactivity
  1. Human (Hu) (4)
  2. Mouse (Ms) (4)
  3. Rat (Rt) (3)
  4. Bovine (Bov) (1)
  5. Canine (Can) (1)
Applications
  1. Western blot / Immunoblot (WB) (4)
  2. Paraffin Sections (P) (2)
  3. Enzyme Immunoassay (E) (1)
Presentation
  1. Aff - Purified (3)
  2. Purified (1)
Host
  1. Rabbit (3)
  2. Goat (1)
Images
  1. 1 image (6)
Images: Applications
  1. Western blot / Immunoblot (WB) (4)
  2. IHC (1)
  3. Paraffin Sections (P) (1)
Species (Protein)
  1. Human (2)
Source
  1. HEK293 cells (1)
  2. SF9 cells (1)
Manufacturer
  1. OriGene Technologies (9)
Service
  • OriGene Technologies GmbH
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  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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