IRF2 antibody
Principal name
IRF2 antibody
Alternative names for IRF2 antibody
Interferon regulatory factor 2, IRF-2
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), EPair for Elisa (EPair)
Background of IRF2 antibody
Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3gamma p48 (the 48 kDa component of the ISGF-3 complex) and IFN consensus sequence-binding protein (ICSBP).
General readings
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)
Lace, M.J., et al. Virology 399(2):270-279(2010)
Masumi, A., et al. Biochem. Biophys. Res. Commun. 391(4):1623-1628(2010)
Daley, D., et al. Hum. Genet. 125(4):445-459(2009)
Dhar, D., et al. PLoS ONE 4 (9), E7049 (2009)















Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA302517 | IRF2 (C-term) antibody |
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| Goat Polyclonal Antibody against IRF2 | |||||||
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Goat | Aff - Purified | Bov, Can, Hu, Ms, Rt | WB |
0.1 mg /
€360.00
|
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| OriGene Technologies, Inc. | |||||||
| TA311964 | IRF2 antibody |
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| Rabbit polyclonal anti-IRF2 antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| AP06668PU-N | IRF2 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | P, WB |
0.1 mg /
€370.00
|
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| OriGene Technologies GmbH | |||||||
+1 additional image |
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| AP52235PU-N | IRF2 (Center) antibody |
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Rabbit | Ig | Aff - Purified | Hu, Ms | WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
+1 additional image |
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+1 additional image
