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Lactoperoxidase antibody

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Principal name

Lactoperoxidase antibody

Alternative names for Lactoperoxidase antibody

LPO, SAPX, Lactoperoxidase, EC=1.11.1.7, Salivary peroxidase, SPO

SwissProt ID

P22079 (Human), P80025 (Bovin)

Gene ID

280844 (LPO), 4025

Ncbi ID

NP_776358, 9606, NM_006151, NM_001160102, NP_006142, NP_001153574.1

Available reactivities

Bov (Bovine), Hu (Human), Gt (Goat), Ms (Mouse), Sh (Sheep), Can (Canine), Rt (Rat), Prim (Primate)

Available hosts

Sheep, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Dot blot (Dot), Immunodiffusion (ID), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Radioimmunoassay (R)

Background of Lactoperoxidase antibody

Lactoperoxidase (LPO) is a heme-containing glycoprotein enzyme of about 78 kD molecular size expressed highly in mammary gland, salivary gland and bronchial submucosal glands, and consequently found in large amounts in secretory fluids such as milk, tears, saliva, and lung fluids. Lactoperoxidase belongs to mammalian peroxidase family with a prosthetic heme group covalently linked to the proteins and other members of this family include myeloperoxidase (MPO), eosinophil peroxidase (EPO), and thyroid peroxidase (TPO). In the presence of H2O2, lactoperoxidase oxidizes thiocyate (SCN-) more efficiently than other peroxidases, whereas MPO, EPO, and TPO most efficiently oxidize chloride, bromide, and iodide, respectively, to form hypo(pseudo)halides. After extracellular transport, SCN- gets oxidized either by peroxidases to form hypothiocyanite (OSCN-) or nonenzymatically by hypochlorite (OCl-). SCN exporters are the cystic fibrosis transmembrane conductance regulators, calcium-activated chloride channels, and pendrin/Slc26A4. OSCN- is tissue-innocuous but has a broad-spectrum microbicidal and microbistatic activity.

General readings

1. Everse J, Coates PW.
The cytotoxic activity of lactoperoxidase: enhancement and inhibition by neuroactive compounds.
Free Radic Biol Med. 2004 Sep 15;37(6):839-49.
PMID: 15384204

PAB11546 - Lactoperoxidase
LPO polyclonal antibody ( Cat # PAB11546 ) ( 0.01 µg/ml ) staining of human lung lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence.
PAB12397 - Lactoperoxidase
Western blot analysis of LPO in MDA-MB-231 cell lysate using LPO polyclonal antibody ( Cat # PAB12397 ).
PAB12398 - Lactoperoxidase
Western blot analysis of LPO in MDA-MB-231 cell lysate using LPO polyclonal antibody ( Cat # PAB12398 ).
TP318093 - Lactoperoxidase
TA305848 - Lactoperoxidase
TA305848 (0.01ug/ml) staining of Human Lung lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
TA336542 - Lactoperoxidase
Western Blot: Lactoperoxidase Antibody [TA336542] - Detection of LPO in MDA-MB231 cell lysate using TA336542.
TA336543 - Lactoperoxidase
Western Blot: Lactoperoxidase Antibody [TA336543] - Detection of LPO in MDA-MB231 cell lysate

2 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Lactoperoxidase antibody
  Rabbit Polyclonal Lactoperoxidase Antibody  
Western Blot: Lactoperoxidase Antibody [TA336542] - Detection of LPO in MDA-MB231 cell lysate using TA336542. Rabbit Purified Bov, Hu, Prim WB
0.1 ml / €415.00
  OriGene Technologies, Inc.

Lactoperoxidase antibody
  Rabbit Polyclonal Lactoperoxidase Antibody  
Western Blot: Lactoperoxidase Antibody [TA336543] - Detection of LPO in MDA-MB231 cell lysate Rabbit Purified Bov, Gt, Hu, Ms, Sh WB
0.1 ml / €300.00
  OriGene Technologies, Inc.

2 Item(s)

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Product Type
  1. Primary Antibody (2)
Clonality
  1. Polyclonal (2)
Target
  1. Lactoperoxidase (2)
Reactivity
  1. Bovine (Bov) (2)
  2. Human (Hu) (2)
  3. Goat (Gt) (1)
  4. Mouse (Ms) (1)
  5. Primate (Prim) (1)
  6. Sheep (Sh) (1)
Applications
  1. Western blot / Immunoblot (WB) (2)
Host
  1. Rabbit (2)
Images
  1. 1 image (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (2)
Manufacturer
  1. OriGene Technologies (2)
Service
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