PLVAP antibody
Principal name
PLVAP antibody
Alternative names for PLVAP antibody
Plasmalemma vesicle protein 1, PV1, PV-1, MECA-32 antigen, FELS, Endothelial cell marker, Endothelial cell surface marker, Endothelial Cell Antigen, Plasmalemma vesicle-associated protein, Fenestrated endothelial-linked structure protein
Ncbi ID
9606, NP_112600, NP_112600.1, NM_031310, NM_032398, NM_020086, NP_115774.2
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P)
Background of PLVAP antibody
PLVAP is a 60kD protein which is otherwise known as MECA-32 and PV-1. PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae. In adult and embryonic mice, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, cardiac and brain tissues. In embryonic mice, PLVAP expression, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated. In humans, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, including glioblastoma and metastatic carcinoma, as well as other cerebral disorders associated with blood-brain barrier disruption, such as acute ischemia. PLVAP represents a novel marker of brain tumour angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target.
General readings
Keuschnigg, J., et al. Blood 114(2):478-484(2009)
Carson-Walter, E.B., et al. Clin. Cancer Res. 11(21):7643-7650(2005)
Strickland, L.A., et al. J. Pathol. 206(4):466-475(2005)
Stan, R.V., et al. Mol. Biol. Cell 15(8):3615-3630(2004)
Hnasko, R., et al. J. Endocrinol. 175(3):649-661(2002)
Stan, R.V., et al. Genomics 72(3):304-313(2001)
Stan, R.V., et al. J. Cell Biol. 145(6):1189-1198(1999)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AM05595BT-N | PLVAP antibody |
||||||
 |
Rat | IgG2a | MECA-32 | Biotin | Ms | C, F |
0.1 mg /
€400.00
|
| OriGene Technologies GmbH | |||||||
| AM05595PU-L | PLVAP antibody |
||||||
|
Rat | IgG2a | MECA-32 | Purified | Ms | C, F |
0.25 mg /
€460.00
|
| OriGene Technologies GmbH | |||||||
| AM05595PU-N | PLVAP antibody |
||||||
|
Rat | IgG2a | MECA-32 | Purified | Ms | C, F |
0.1 mg /
€330.00
|
| OriGene Technologies GmbH | |||||||
| AM05595PU-T | PLVAP antibody |
||||||
|
Rat | IgG2a | MECA-32 | Purified | Ms | C, F |
25 µg /
€180.00
|
| OriGene Technologies GmbH | |||||||
| AM26203FC-N | PLVAP antibody |
||||||
|
Mouse | IgG1 | 174/2 | FITC | Hu | C, ICC/IF, WB |
0.1 mg /
€500.00
|
| OriGene Technologies GmbH | |||||||
| AM26203PU-N | PLVAP antibody |
||||||
|
Mouse | IgG1 | 174/2 | Purified | Hu | C, ICC/IF, WB |
0.1 mg /
€450.00
|
| OriGene Technologies GmbH | |||||||
| AP53357PU-N | PLVAP (Center) antibody |
||||||
 |
Rabbit | Ig | Aff - Purified | Hu | F, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
 +1 additional image |
|||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP308914 | PLVAP |
||||
| Recombinant protein of human plasmalemma vesicle associated protein (PLVAP) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY410560 | PLVAP overexpression lysate |
|
|
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. |
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR206983L2V | Lenti ORF particles, Plvap (GFP-tagged) - Mouse plasmalemma vesicle associated protein (Plvap), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,100.00
|
|
| OriGene Technologies, Inc. | ||
| MR206983L1V | Lenti ORF particles, Plvap (Myc-DDK-tagged) - Mouse plasmalemma vesicle associated protein (Plvap), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€990.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR206823L2V | Lenti ORF particles, Plvap (GFP-tagged ORF) - Rat plasmalemma vesicle associated protein (Plvap), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,100.00
|
|
| OriGene Technologies, Inc. | ||
| RR206823L1V | Lenti ORF particles, Plvap (Myc-DDK-tagged ORF) - Rat plasmalemma vesicle associated protein (Plvap), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€980.00
|
|
| OriGene Technologies, Inc. | ||