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PTP4A2 antibody

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Principal name

PTP4A2 antibody

Alternative names for PTP4A2 antibody

PRL2, PRL-2, PTPCAAX2, HU-PP-1, OV-1, Protein-tyrosine phosphatase 4a2, Protein tyrosine phosphatase type IVA 2, Protein-tyrosine phosphatase of regenerating liver 2

SwissProt ID

O70274 (Mouse), Q12974 (Human), Q6P9X4 (Rat)

Gene ID

8073 (PTP4A2), 19244 (Ptp4a2), 85237

Ncbi ID

NP_001182029.1, 9606, NP_536316, NM_080391, NP_001158217.1, NM_053475, NM_001195101

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of PTP4A2 antibody

The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell sigling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-termil prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-termil prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II); and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype; which suggested its role in tumorigenesis. Altertively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11; 12 and 17.?

General readings

Si X., et al. (2001) J Biol chem. 246(35):32875-82.
Werner SR., et al. (2003) Cancer Lett. 202(2):201-11.

AR09643PU-L - PTP4A2
AR09643PU-L - PTP4A2
Recombinant human PTP4A2, 1- 167 aa, His-tagged
TP309983 - PTP4A2
TA324078 - PTP4A2
Predicted band size: 19 kDa . Positive control: Jurkat cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 50 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds)
TA324079 - PTP4A2
Predicted band size: 19kDa. Positive control: Hela, Jurkat and SKOV3 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: Hela cell lysate Lane2: Jurkat cell lysate Lane3: SKOV3 cell lysate Lysates: 50 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 30 seconds)
TA324079 - PTP4A2
Predicted cell location: Cytoplasm. Positive control: Human colon cancer tissue . Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human colon cancer tissue using PTP4A2 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification:x200)
TA324871 - PTP4A2
PTP4A2 Antibody (Center) (Cat. #TA324871) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the PTP4A2 antibody detected the PTP4A2 protein (arrow).
TA324871 - PTP4A2
Formalin-fixed and paraffin-embedded human prostate carcinoma with PTP4A2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
TA324871 - PTP4A2
Immunofluorescence analysis of PTP4A2 Antibody (Center) with paraffin-embedded human prostate carcinoma tissue . 0.05 mg/ml primary antibody was followed by FITC-conjugated goat anti-rabbit lgG (whole molecule). FITC emits green fluorescence.Red counterstaining is PI.
TA324871 - PTP4A2
Flow cytometric analysis of widr cells using PTP4A2 Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTP4A2 antibody
  Anti-PTP4A2 Rabbit Polyclonal Antibody  
Predicted band size: 19 kDa . Positive control: Jurkat cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 50 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

PTP4A2 antibody
  Anti-PTP4A2 rabbit polyclonal antibody  
Predicted band size: 19kDa. Positive control: Hela, Jurkat and SKOV3 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: Hela cell lysate Lane2: Jurkat cell lysate Lane3: SKOV3 cell lysate Lysates: 50 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/8000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

PTP4A2 (Center) antibody
  Rabbit polyclonal PTP4A2 Antibody (Center)  
PTP4A2 Antibody (Center) (Cat. #TA324871) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the PTP4A2 antibody detected the PTP4A2 protein (arrow). Rabbit Hu WB
0.4 ml / €415.00
  OriGene Technologies, Inc.
+3 additional images

PTP4A2 antibody
  Rabbit Polyclonal Anti-PTP4A2 Antibody  
PTP4A2 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTP4A2 (transcript variant 1)
  Recombinant protein of human protein tyrosine phosphatase type IVA, member 2 (PTP4A2), transcript variant 1  
PTP4A2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

Lysates

Catalog No.    

PTP4A2 overexpression lysate
PTP4A2 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ptp4a2 (GFP-tagged ORF) - Rat protein tyrosine phosphatase 4a2 (Ptp4a2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Ptp4a2 (GFP-tagged ORF) - Rat protein tyrosine phosphatase 4a2 (Ptp4a2), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Ptp4a2 (Myc-DDK-tagged ORF) - Rat protein tyrosine phosphatase 4a2 (Ptp4a2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Ptp4a2 (Myc-DDK-tagged ORF) - Rat protein tyrosine phosphatase 4a2 (Ptp4a2), 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

8 Item(s)

per page

Available Filters

Product Type
  1. Lysate (1)
  2. Primary Antibody (4)
  3. Protein | Growth Factor (1)
  4. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (4)
Target
  1. PTP4A2 (5)
Property
  1. Center (1)
Reactivity
  1. Human (Hu) (4)
  2. Mouse (Ms) (3)
  3. Rat (Rt) (3)
Applications
  1. Western blot / Immunoblot (WB) (4)
  2. Enzyme Immunoassay (E) (3)
  3. Paraffin Sections (P) (2)
Presentation
  1. Purified (3)
Host
  1. Rabbit (4)
Images
  1. 1 image (4)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
  2. IHC (2)
  3. Immunofluorescence (IF) (1)
Species (Protein)
  1. Human (1)
Source
  1. HEK293 cells (1)
Manufacturer
  1. OriGene Technologies (8)
Service
  • OriGene Technologies GmbH
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  • Germany
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  • fax: +49-5221-34606-11
  • email: info-de@origene.com
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