PTPRM antibody
Principal name
PTPRM antibody
Alternative names for PTPRM antibody
PTPRL1, R-PTP-mu, RPTPU, Receptor-type tyrosine-protein phosphatase mu, Protein-tyrosine phosphatase mu
Ncbi ID
9606, NP_001098714.1, AAH51651.1, NM_001105244, NP_033010.2, BC058614, NM_008984, NM_002845
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of PTPRM antibody
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be sigling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitotic cycle; and oncogenic transformation. This PTP possesses an extracellular region; a single transmembrane region; and two tandem catalytic domains; and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain; an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1; which may be necessary for the downstream sigling in response to cell-cell adhesion. Altertive splicing results in multiple transcripts encoding distinct isoforms.
Anti-PTPRM antibody IHC of human retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTPRM antibody IHC of human retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Predicted cell location: Cytoplasm. Positive control: Human breast and lung cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human breast and lung cancer tissue using PTPRM antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x 200)
Predicted cell location: Cytoplasm. Positive control: Human breast and lung cancer tissue. Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human breast and lung cancer tissue using PTPRM antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x200)
Predicted cell location: Cytoplasm. Positive control: Human esophagus and ovarian cancer tissue. Recommended dilution: 1/100-300 The image on the left is immunohistochemistry of paraffin-embedded human esophagus cancer tissue using PTPRM antibody at dilution 1/80, on the right is treated with the synthetic peptide. (Original magnification:x 200)
Predicted cell location: Cytoplasm. Positive control: Human esophagus and ovarian cancer tissue. Recommended dilution: 1/100-300 The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using PTPRM antibody at dilution 1/80, on the right is treated with the synthetic peptide. (Original magnification:x200)
Anti-PTPRM antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-PTPRM antibody IHC of human eye, retina. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Host: Rabbit; Target Name: PTPRM; Sample Tissue: 293T Whole Cell lysates; Antibody Dilution: 1.0 ug/ml
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA317226 | PTPRM (Internal Region) antibody |
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| PTPRM Rabbit Polyclonal (Internal) Antibody | |||||||
 |
Rabbit | Aff - Purified | Bear, Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, Mky, Ms, Op, Prim, Rb, Rt | P |
50 µg /
€425.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA317227 | PTPRM (Internal Region) antibody |
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| PTPRM Rabbit Polyclonal (Internal) Antibody | |||||||
|
Rabbit | Aff - Purified | Bear, Bov, Bt, Eq, Hst, Hu, Mky, Ms, Op, Prim, Rb, Rt | P |
50 µg /
€425.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA322946 | PTPRM antibody |
||||||
| Anti-PTPRM Rabbit Polyclonal Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
 +1 additional image |
|||||||
| TA322947 | PTPRM antibody |
||||||
| Anti-PTPRM Rabbit Polyclonal Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| +1 additional image |
|||||||
| TA341072 | PTPRM antibody |
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| Rabbit Polyclonal Anti-PTPRM Antibody (Internal) | |||||||
 |
Rabbit | Purified | Hu |
50 µg /
€425.00
|
|||
| OriGene Technologies, Inc. | |||||||
| TA341078 | PTPRM antibody |
||||||
| Rabbit Polyclonal Anti-PTPRM Antibody (Internal) | |||||||
 |
Rabbit | Purified | Bov, Hu, Ms, Xen |
50 µg /
€425.00
|
|||
| OriGene Technologies, Inc. | |||||||
| AM05259PU-N | PTPRM antibody |
||||||
|
Mouse | IgG1 | SBK10 | Purified | Bov, Hu, Ms, Rt | WB |
0.1 mg /
€400.00
|
| OriGene Technologies GmbH | |||||||
CRISPR
| Catalog No. | Species | Donor Vector | |
|---|---|---|---|
| KN219912 | PTPRM - human gene knockout kit via CRISPR |
||
|
Human | GFP-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN219912BN | PTPRM - human gene knockout kit via CRISPR |
||
|
Human | mBFP-Neo |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN219912LP | PTPRM - human gene knockout kit via CRISPR |
||
|
Human | Luciferase-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN219912RB | PTPRM - human gene knockout kit via CRISPR |
||
|
Human | RFP-BSD |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
Lysates
| Catalog No. | ||
|---|---|---|
| LY426233 | PTPRM overexpression lysate |
|
|
0.1 mg /
€495.00
|
|
| OriGene Technologies, Inc. |
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC219912L2V | Lenti ORF particles, PTPRM (mGFP-tagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 2, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,680.00
|
|
| OriGene Technologies, Inc. | ||
| RC219912L1V | Lenti ORF particles, PTPRM (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 2, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,420.00
|
|
| OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR211395L2V | Lenti ORF particles, Ptprm (GFP-tagged) - Mouse protein tyrosine phosphatase, receptor type, M (cDNA clone MGC:60661 IMAGE:30056619), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,470.00
|
|
| OriGene Technologies, Inc. | ||
| MR211395L1V | Lenti ORF particles, Ptprm (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, receptor type, M (cDNA clone MGC:60661 IMAGE:30056619), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,330.00
|
|
| OriGene Technologies, Inc. | ||
