PTPRM antibody
Principal name
PTPRM antibody
Alternative names for PTPRM antibody
PTPRL1, R-PTP-mu, RPTPU, Receptor-type tyrosine-protein phosphatase mu, Protein-tyrosine phosphatase mu
Ncbi ID
9606, NP_001098714.1, AAH51651.1, NM_001105244, NP_033010.2, BC058614, NM_008984, NM_002845
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of PTPRM antibody
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be sigling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitotic cycle; and oncogenic transformation. This PTP possesses an extracellular region; a single transmembrane region; and two tandem catalytic domains; and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain; an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1; which may be necessary for the downstream sigling in response to cell-cell adhesion. Altertive splicing results in multiple transcripts encoding distinct isoforms.
Lysates
| Catalog No. | ||
|---|---|---|
| LY426233 | PTPRM overexpression lysate |
|
 |
0.1 mg /
€495.00
|
|
| OriGene Technologies, Inc. |
