RAG2 antibody
Principal name
RAG2 antibody
Alternative names for RAG2 antibody
RAG-2, V(D)J recombination-activating protein 2
SwissProt ID
O13034 (Danre), P21784 (Mouse), P25022 (Chick), P34089 (Rabit), P55895 (Human), Q91830 (Xenla)
Ncbi ID
Available reactivities
Available hosts
Available applications
ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Enzyme Immunoassay (E), Paraffin Sections (P)
Background of RAG2 antibody
This gene encodes a protein that is involved in the initiation of V(D)J recombition during B and T cell development. This protein forms a complex with the product of the adjacent recombition activating gene 1, and this complex can form double-strand breaks by cleaving D at conserved recombition sigl sequences. The recombition activating gene 1 component is thought to contain most of the catalytic activity, while the N-termil of the recombition activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with D. A C-termil plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodeficiency associated with autoimmune-like symptoms. [provided by RefSeq]
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Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA307957 | RAG2 antibody |
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| Rabbit polyclonal antibody to RAG2 (recombination activating gene 2) | |||||||
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Rabbit | IgG | Aff - Purified | Hu, Rt | ICC/IF, P, WB |
0.1 ml /
€415.00
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| OriGene Technologies, Inc. | |||||||
 +3 additional images |
Highly validated antibody! |
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