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RNF216 antibody

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Principal name

RNF216 antibody

Alternative names for RNF216 antibody

RING finger protein 216, TRIAD3, UBCE7IP1, ZIN, E3 ubiquitin-protein ligase RNF216, Triad domain-containing protein 3, Zinc finger protein inhibiting NF-kappa-B, Ubiquitin-conjugating enzyme 7-interacting protein 1

SwissProt ID

P58283 (Mouse), Q8C1U3 (Mouse), Q9NWF9 (Human)

Gene ID

54476 (RNF216), 108086 (Rnf216)

Ncbi ID

NP_996994.1, 9606, 5874, 10090, CAL37508.1, AAP47174, NM_207110, NM_207116, NM_207111

Available reactivities

Ms (Mouse), Hu (Human), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of RNF216 antibody

Activation of NF-kappaB as a result of Toll-like receptor (TLR) and IL-1 receptor signaling is a major component of innate immune responses (reviewed in 1). Signals from these receptors are relayed by a number of adapter molecules such as TRIF, TIRAP, and MyD88 (2). Several regulatory mechanisms exist to control TLR signal transduction, including the inhibition of TLR expression and signaling by molecules such as ST2 and SIGIRR (3,4). Another mechanism is by the ubi-quitinization of selected TLRs by TRIAD3A, an E3 ubiquitin-protein ligase (5). TRIAD3A is a RING finger protein that can bind to TLR4 and TLR9, and to a lesser extent TLR3 and TLR5, catalyzing the ubiquitization of these molecules. Overexpression of TRIAD3A promoted the nearly complete degradation of TLR4 and TLR9; this reduction was reflected in the decreased signal-specific activation by ligands specific for these TLRs. Conversely, depletion of TRIAD3A resulted in enhanced TLR activation (5).

SP2172P - RNF216
Formalin fixed, paraffin embedded mouse heart stained with Rabbit anti Mouse TRIAD3A (SP2172P) following antigen retrieval using sodium citrate buffer (pH6.0)
SP2172P - RNF216
Western blot analysis of mouse heart lysate probed with Rabbit anti Mouse TRIAD3A (SP2172P) at 0.5(A), 1(B) and 2(C) µg/ml
AP05247PU-N - RNF216
Western blot analysis of TRIAD3A in mouse heart cell lysates with TRIAD3A antibody at (A) 0.5, (B) 1, and (C) 2 µg/ml
AP07382PU-N - RNF216
Testis: Formalin-Fixed Paraffin-Embedded (FFPE)
PAB1762 - RNF216
Formalin-fixed and paraffin-embedded human cancer tissue reacted with RNF216 polyclonal antibody ( Cat # PAB1762 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
PAB1762 - RNF216
The RNF216 polyclonal antibody ( Cat # PAB1762 ) is used in Western blot to detect RNF216 in mouse kidney tissue lysate.
AP11957PU-N - RNF216
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
AP11957PU-N - RNF216
The anti-UBCE7IP1 (AP11957PU-N) is used in Western blot to detect UBCE7IP1 in mouse kidney tissue lysate.
PAB12931 - RNF216
Immunohistochemistry of Rnf216 in mouse heart with Rnf216 polyclonal antibody ( Cat # PAB12931 ) at 10 µg/ml.
PAB12931 - RNF216
Western blot analysis of Rnf216 in mouse heart tissue lysates with Rnf216 polyclonal antibody ( Cat # PAB12931 ) at ( A ) 0.5, ( B ) 1, and ( C ) 2 µg/ml.
PAB9789 - RNF216
Western blot analysis of Rnf216 expression in mouse heart tissue with Rnf216 polyclonal antibody at 0.5 µg/ml.
AP08481PU-N - RNF216
Liver: Formalin-Fixed Paraffin-Embedded (FFPE)
TA306182 - RNF216
Western blot analysis of TRIAD3A in mouse heart cell lysates with TRIAD3A antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml.
TA306182 - RNF216
Immunohistochemistry of TRIAD3A in mouse heart with TRIAD3A antibody at 10 ug/ml.
TA306182 - RNF216
Immunofluorescence of TRIAD3A in Mouse Heart cells with TRIAD3A antibody at 20 ug/mL.
TA344581 - RNF216
Host: Rabbit; Target Name: Rnf216; Sample Tissue: Mouse Thymus lysates; Antibody Dilution: 1.0 ug/ml

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

RNF216 antibody
  Rabbit Polyclonal TRIAD3A Antibody  
Western blot analysis of TRIAD3A in mouse heart cell lysates with TRIAD3A antibody at (A) 0.5, (B) 1, and (C) 2 ug/ml. Rabbit IgG Purified Hu, Ms E, P, WB
0.1 mg / €415.00
  OriGene Technologies, Inc.
+2 additional images

RNF216 (Isoform 1) antibody
Western blot analysis of TRIAD3A in mouse heart cell lysates with TRIAD3A antibody at (A) 0.5, (B) 1, and (C) 2 µg/ml Rabbit IgG Purified Ms WB
0.1 mg / €600.00
  OriGene Technologies GmbH

RNF216 antibody
Testis: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms P, WB
50 µg / €425.00
  OriGene Technologies GmbH

RNF216 (350-400) antibody
Liver: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu P, WB
50 µg / €425.00
  OriGene Technologies GmbH

RNF216 (C-term) antibody
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €415.00
  OriGene Technologies GmbH
+1 additional image

RNF216 (N-term) antibody
Formalin fixed, paraffin embedded mouse heart stained with Rabbit anti Mouse TRIAD3A (SP2172P) following antigen retrieval using sodium citrate buffer (pH6.0) Rabbit Purified Ms P, WB
0.1 mg / €410.00
  OriGene Technologies GmbH
+1 additional image

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, RNF216 (mGFP-tagged)-Human ring finger protein 216 (RNF216), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, RNF216 (mGFP-tagged)-Human ring finger protein 216 (RNF216), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,040.00
  OriGene Technologies, Inc.
 

7 Item(s)

per page

Available Filters

Product Type
  1. Human Lenti ORF Particle (1)
  2. Primary Antibody (6)
Clonality
  1. Polyclonal (6)
Target
  1. RNF216 (6)
Property
  1. 350-400 (1)
  2. C-term (1)
  3. Isoform 1 (1)
  4. N-term (1)
Reactivity
  1. Mouse (Ms) (5)
  2. Human (Hu) (4)
Applications
  1. Western blot / Immunoblot (WB) (6)
  2. Paraffin Sections (P) (5)
  3. Enzyme Immunoassay (E) (1)
Presentation
  1. Purified (5)
  2. Aff - Purified (1)
Host
  1. Rabbit (6)
Images
  1. 1 image (6)
  2. 3+ images (1)
Images: Applications
  1. Paraffin Sections (P) (4)
  2. Western blot / Immunoblot (WB) (4)
  3. Immunofluorescence (IF) (1)
  4. IHC (1)
Manufacturer
  1. OriGene Technologies (7)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
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