Home » Target » TP53I11 antibody

TP53I11 antibody

Principal name

TP53I11 antibody

Alternative names for TP53I11 antibody

p53-induced gene 11 protein, PIG11, Tumor protein p53-inducible protein 11

SwissProt ID

O14683 (Human)

Gene ID

9537 (TP53I11)

Ncbi ID

NP_001070255.1, NM_006034, NP_006025

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of TP53I11 antibody

TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.

Figure 1. AP07986PU-N TP53I11 Antibody Staining of Formalin-Fixed Paraffin-Embedded Human Brain Cerebellum at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

AP07986PU-N

Western blot was performed using 100 µg colon carcinoma whole cell extract ( HCT-116 ) and TP53K372me1 polyclonal antibody ( Cat # PAB14117 ), diluted 1 : 200 in TBS-Tween containing 5% skimmed milk.

PAB14117

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TP53I11 Antibody. The picture on the right is treated with the synthesized peptide.

Western blot analysis of extracts from HuvEc cells, using TP53I11 Antibody. The lane on the right is treated with the synthesized peptide.

Immunofluorescent analysis of PIG11 staining in HuvEc cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).

Western blot analysis of PIG11 expression in HuvEc (A) whole cell lysates.

TP307402

Western blot analysis of extracts from HUVEC cells, using TP53I11 antibody.The lane on the right is treated with the synthesized peptide.

TA314930

Immunohistochemistry analysis of paraffin-embedded human brain tissue using TP53I11 antibody.The picture on the right is treated with the synthesized peptide.

TA314930

Western blot analysis on HuvEc cell lysate using TP53I11 Antibody

TA347520

Primary Antibodies

Catalog No.	Host	Iso.	Pres.	React.	Applications
TA314930	TP53I11 antibody
	Rabbit polyclonal anti-TP53I11 antibody
	Rabbit	IgG	Purified	Hu	E, P, WB	0.1 ml / €335.00
						OriGene Technologies, Inc.
+1 additional image
TA347520	TP53I11 antibody
	Rabbit Polyclonal Anti-TP53I11 Antibody
	Rabbit	IgG	Purified	Hu	WB	0.1 mg / €335.00
						OriGene Technologies, Inc.
TA351835	TP53I11 antibody
	Rabbit Polyclonal Anti-TP53I11 Antibody
	Rabbit	IgG	Purified	Hu, Ms, Rt	E, P, WB	0.1 ml / €335.00
						OriGene Technologies, Inc.
AP07986PU-N	TP53I11 (179-189) antibody
	Rabbit		Purified	Hu	E, P	50 µg / €425.00
						OriGene Technologies GmbH

Antibodies (see all»)

Kits (see all»)

Antigens

Lysates (see all»)

Tissue Slides (see all»)

Other life-science products