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TYK2 antibody

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Principal name

TYK2 antibody

Alternative names for TYK2 antibody

JTK1, Non-receptor tyrosine-protein kinase TYK2

SwissProt ID

P29597 (Human), Q9R117 (Mouse)

Gene ID

7297 (TYK2)

Ncbi ID

9606, NP_003322.3, NP_003322, NM_003331

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of TYK2 antibody

Tyk 2 belongs to the family of non-receptor janus tyrosine kinases, which regulate a spectrum of cellular functions occurring downstream of activated cytokine receptors in the lympho-hematopoietic system. Immunological stimuli, such as interferons and cytokines, recruit STAT transcription factors to the cytokine receptor where Tyk 2 is associated. Tyk 2 then phosphorylates proximal STAT factors, which subsequently dimerize, translocate to the nucleus, and bind to cis elements upstream of target gene promoters to regulating transcription. The canonical JAK-STAT pathway is integral to maintaining a normal immune system by stimulating proliferation, differentiation, survival, and host resistance to pathogens. Cytokine induced pro-inflammatory responses are attractive targets for anti-inflammatory therapies, specifically at the level of Jak-STAT signaling.

H00007297-M01 - TYK2
Immunoperoxidase of monoclonal antibody to TYK2 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3 ug/ml]
H00007297-M01 - TYK2
Immunofluorescence of monoclonal antibody to TYK2 on HeLa cell. [antibody concentration 10 ug/ml]
H00007297-M01 - TYK2
Western Blot analysis of TYK2 expression in transfected 293T cell line by TYK2 monoclonal antibody (M01), clone 6G12.Lane 1: TYK2 transfected lysate(133.7 KDa).Lane 2: Non-transfected lysate.
H00007297-M01 - TYK2
TYK2 monoclonal antibody (M01), clone 6G12 Western Blot analysis of TYK2 expression in HeLa ( Cat # L013V1 ).
H00007297-M02 - TYK2
Immunoperoxidase of monoclonal antibody to TYK2 on formalin-fixed paraffin-embedded human leiomyosarcoma. [antibody concentration 3 ug/ml]
H00007297-M02 - TYK2
Immunofluorescence of monoclonal antibody to TYK2 on HeLa cell. [antibody concentration 10 ug/ml]
H00007297-M02 - TYK2
TYK2 monoclonal antibody (M02), clone 5A4 Western Blot analysis of TYK2 expression in Hela NE ( Cat # L013V3 ).
H00007297-M03 - TYK2
Immunoperoxidase of monoclonal antibody to TYK2 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml]
H00007297-M03 - TYK2
Immunoperoxidase of monoclonal antibody to TYK2 on formalin-fixed paraffin-embedded human lymphoma. [antibody concentration 3 ug/ml]
H00007297-M03 - TYK2
TYK2 monoclonal antibody (M03), clone 6H1 Western Blot analysis of TYK2 expression in Hela NE ( Cat # L013V3 ).
H00007297-M03 - TYK2
Detection limit for recombinant GST tagged TYK2 is approximately 1ng/ml as a capture antibody.
AP02648PU-S - TYK2
Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using TYK2 antibody AP02648PU.
AP07435PU-N - TYK2
Kidney: Formalin-Fixed Paraffin-Embedded (FFPE)
AP08010PU-N - TYK2
Figure 1. Western blot analysis of extracts from HT-29 cells untreated or treated with Anisomycin (20min), using TYK2 (pTyr1054) antibody AP08010PU (Lane 1 and 2).
H00007297-D01P - TYK2
TYK2 MaxPab rabbit polyclonal antibody. Western Blot analysis of TYK2 expression in mouse spleen.
H00007297-D01P - TYK2
Western Blot analysis of TYK2 expression in transfected 293T cell line (H00007297-T02) by TYK2 MaxPab polyclonal antibody.Lane 1: TYK2 transfected lysate(133.70 KDa).Lane 2: Non-transfected lysate.
PAB7734 - TYK2
Western blot analysis of extracts from HT-29 cells treated with anisomycin ( 20 min ) , using TYK2 (phospho Y1054) polyclonal antibody ( Cat # PAB7734 ).
AP21083PU-N - TYK2
Immunohistochemistry (IHC) analyzes of Tyk 2 antibody (Cat.-No.: AP21083PU-N) in paraffin-embedded human breast carcinoma tissue.
AP21083PU-N - TYK2
Western blot (WB) analysis of Tyk 2 antibody (Cat.-No.: AP21083PU-N) in extracts from 293cells.
B7248-1 - TYK2
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TYK2 (Ab-1054) Antibody. The picture on the right is treated with the synthesized peptide.
B7248-1 - TYK2
Immunofluorescence analysis of COS7 cells, using TYK2 (Ab-1054) Antibody. The picture on the right is treated with the synthesized peptide.
B7248-1 - TYK2
Western blot analysis of extracts from 293/COS7 cells, treated with heat shock, using TYK2 (Ab-1054) Antibody. The lane on the right is treated with the synthesized peptide.
ARP30319_P050 - TYK2
Human COLO205; WB Suggested Anti-TYK2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: COLO205 cell lysate; TYK2 antibody - C-terminal region (ARP30319_P050) in Human COLO205 cells using Western Blot
AM06139SU-N - TYK2
Western blot analysis using TYK2 antibody Cat.-No AM06139SU-N against truncated TYK2 recombinant protein (Lane 1) and Jurkat cell lysate (Lane 2).
TA308735 - TYK2
Sample(30 ug whole cell lysate). A:H1299. B:HeLa S3. 5% SDS PAGE. TA308735 diluted at 1:1000
TA308735 - TYK2
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TYK2(TA308735) antibody at 1:200 dilution.
TA319732 - TYK2
Western blot analysis of TYK2 in human small intestine tissue lysate with TYK2 antibody at (A) 1 and (B) 2 ug/mL
TA321570 - TYK2
Predicted band size: 134 kDa . Positive control: Raji cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
TA347921 - TYK2
Western blot analysis of TYK2 expression in 293 cel
TA329144 - TYK2
WB Suggested Anti-TYK2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: COLO205 cell lysate
TA309989 - TYK2
Western blot analysis of extracts from HT29 cells untreated (Lane 1) or treated (Lane 2) with Anisomycin (20min), using TYK2 (phospho-Tyr1054) antibody.

3 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

TYK2 antibody
Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using TYK2 antibody AP02648PU. Rabbit Aff - Purified P
0.1 mg / €300.00
  OriGene Technologies GmbH

TYK2 antibody
Figure 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using TYK2 antibody AP02648PU. Rabbit Aff - Purified P
50 µg / €230.00
  OriGene Technologies GmbH

TYK2 antibody
Immunohistochemistry (IHC) analyzes of Tyk 2 antibody (Cat.-No.: AP21083PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH
+1 additional image

3 Item(s)

per page

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Product Type
  1. Primary Antibody (3)
Clonality
  1. Polyclonal (3)
Target
  1. TYK2 (3)
Reactivity
  1. Human (Hu) (1)
  2. Mouse (Ms) (1)
Applications
  1. Paraffin Sections (P) (3)
  2. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
  3. Western blot / Immunoblot (WB) (1)
Presentation
  1. Aff - Purified (3)
Host
  1. Rabbit (3)
Images
  1. 1 image (3)
Manufacturer
  1. OriGene Technologies (3)
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