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UGDH antibody

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Principal name

UGDH antibody

Alternative names for UGDH antibody

UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH

SwissProt ID

O60701 (Human), O70199 (Rat), O70475 (Mouse), P12378 (Bovin)

Gene ID

7358 (UGDH), 281564, 22235 (Ugdh), 83472

Ncbi ID

9606, NP_003350, NP_776636, NP_001171629.1, NM_003359, NP_001171629, NM_001184700, NP_033492.1, NM_009466, NM_031325, NM_001184701

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit), Ye (Yeast), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Dot blot (Dot), Immunodiffusion (ID), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Radioimmunoassay (R), Paraffin Sections (P)

Background of UGDH antibody

UDP-GlcDH (also called UDP-glucose 6-dehydrogese, UGDH or UDPGDH) is a member of the UDP-glucose/GDP-mannose dehydrogese family. UDP-GlcDH converts UDP-glucose to UDP-glucuronic acid, which is a crucial component in the biosynthesis of the glycosaminoglycans, hyaluron, heparan sulfate and chondroitin sulfate. Found as common components of the extracellular matrix, these glycosaminoglycans are significant in sigl transduction, cell migration, cancer growth and cancer metastasis. UDP-glucuronic acid (UDP-GlcA) is needed in the liver for the excretion of toxic compounds. UDP-GlcDH is a ubiquitously expressed protein most abundant in the liver. The protein structure of UDP-GlcDH was first alyzed in cow liver and found to be a homohexamer. This structure is well conserved between species and phyla with an overall 97% sequence identity shared between different species of mammals. Research indicates that UDP-GlcDH expression is upregulated by TGF? and downregulated by hypoxia.

General readings

Bontemps Y., et al. (2003) J Biol Chem. 278(24):21566-75.
Vatsyayan J., et al. (2006) Biosci Biotechnol Biochem. 70(2):401-10.

H00007358-B01P - UGDH
UGDH MaxPab polyclonal antibody. Western Blot analysis of UGDH expression in human liver.
H00007358-B01P - UGDH
Western Blot analysis of UGDH expression in transfected 293T cell line (H00007358-T01) by UGDH MaxPab polyclonal antibody.Lane 1: UGDH transfected lysate(54.34 KDa).Lane 2: Non-transfected lysate.
H00007358-B01P - UGDH
UGDH MaxPab polyclonal antibody. Western Blot analysis of UGDH expression in MCF-7.
AR09548PU-L - UGDH
Recombinant human UGDH, 1-494 aa, His-tagged
C19458-1 - UGDH
Western blot analysis of extracts from COLO cells, using UGDH Antibody. The lane on the right is treated with the synthesized peptide.
ARP61247_P050 - UGDH
Human HepG2; WB Suggested Anti-UGDH Antibody. . Titration: 1.0 ug/ml. . Positive Control: HepG2 Whole Cell. UGDH is supported by BioGPS gene expression data to be expressed in HepG2.; UGDH antibody - C-terminal region (ARP61247_P050) in Human HepG2 cells using Western Blot
AP54453PU-N - UGDH
UGDH Antibody (C-term) (AP54453PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of UGDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
AP54453PU-N - UGDH
UGDH Antibody (C-term) (AP54453PU-N) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the UGDH antibody detected the UGDH protein (arrow).
TP302132 - UGDH
TA314662 - UGDH
Western blot analysis of extracts from COLO cells, using UGDH antibody.The lane on the right is treated with the synthesized peptide.
TA326998 - UGDH
Western blot analysis of HepG2 cell and HeLa cell lysate using UGDH antibody.
TA326998 - UGDH
Immunohistochemistry of paraffin-embedded rat kidney using UGDH antibody at dilution of 1:200 (400x lens).
TA326998 - UGDH
Immunohistochemistry of paraffin-embedded human esophageal cancer using UGDH antibody at dilution of 1:200 (400x lens).
TA326998 - UGDH
Immunofluorescence analysis of HeLa cell using UGDH antibody. Blue: DAPI for nuclear staining.
TA343136 - UGDH
Host: Rabbit; Target Name: Ugdh; Sample Tissue: Rat Stomach lysates; Antibody Dilution: 1.0 ug/ml
  1. Quick-Filters:
  2. Highly Validated (1)

11 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

UGDH antibody
  Rabbit anti-UGDH Polyclonal Antibody  
Western blot analysis of HepG2 cell and HeLa cell lysate using UGDH antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €335.00
  OriGene Technologies, Inc.
+3 additional images

Highly validated antibody!

UGDH antibody
  Rabbit polyclonal anti-UGDH antibody  
Western blot analysis of extracts from COLO cells, using UGDH antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

UGDH (C-term) antibody
UGDH Antibody (C-term) (AP54453PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of UGDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €415.00
  OriGene Technologies GmbH
+1 additional image

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

UGDH
  Recombinant protein of human UDP-glucose dehydrogenase (UGDH)  
UGDH Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

Lysates

Catalog No.    

UGDH overexpression lysate
UGDH overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

UGDH overexpression lysate
UGDH overexpression lysate  
0.1 mg / €315.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, UGDH (Myc-DDK-tagged)-Human UDP-glucose 6-dehydrogenase (UGDH), transcript variant 3, 200 uL, >10^7 TU/mL
Lenti ORF particles, UGDH (Myc-DDK-tagged)-Human UDP-glucose 6-dehydrogenase (UGDH), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,000.00
  OriGene Technologies, Inc.
 

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ugdh (GFP-tagged) - Mouse UDP-glucose dehydrogenase (Ugdh), 200 uL, >10^7 TU/mL
Lenti ORF particles, Ugdh (GFP-tagged) - Mouse UDP-glucose dehydrogenase (Ugdh), 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Ugdh (Myc-DDK-tagged) - Mouse UDP-glucose dehydrogenase (Ugdh), 200 uL, >10^7 TU/mL
Lenti ORF particles, Ugdh (Myc-DDK-tagged) - Mouse UDP-glucose dehydrogenase (Ugdh), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.
 

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ugdh (GFP-tagged ORF) - Rat UDP-glucose dehydrogenase (Ugdh), 200 uL, >10^7 TU/mL
Lenti ORF particles, Ugdh (GFP-tagged ORF) - Rat UDP-glucose dehydrogenase (Ugdh), 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Ugdh (Myc-DDK-tagged ORF) - Rat UDP-glucose dehydrogenase (Ugdh), 200 uL, >10^7 TU/mL
Lenti ORF particles, Ugdh (Myc-DDK-tagged ORF) - Rat UDP-glucose dehydrogenase (Ugdh), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.
 

11 Item(s)

per page
11 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. Human Lenti ORF Particle (1)
  2. Lysate (2)
  3. Mouse Lenti ORF Particle (2)
  4. Primary Antibody (3)
  5. Protein | Growth Factor (1)
  6. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (3)
Target
  1. UGDH (4)
Property
  1. C-term (1)
Reactivity
  1. Human (Hu) (3)
  2. Mouse (Ms) (2)
  3. Rat (Rt) (2)
Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Enzyme Immunoassay (E) (1)
  3. Paraffin Sections (P) (1)
Presentation
  1. Purified (2)
  2. Aff - Purified (1)
Host
  1. Rabbit (3)
Images
  1. 1 image (4)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Immunofluorescence (IF) (1)
  3. IHC (1)
  4. Paraffin Sections (P) (1)
Species (Protein)
  1. Human (1)
Source
  1. HEK293 cells (1)
Manufacturer
  1. OriGene Technologies (11)
Service
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