Switch to Europe/Worldwide website Switch to German website Switch to French website Switch to OriGene Technologies, Inc. (North America)
Home » Target » UGDH antibody

UGDH antibody

(reset)

Principal name

UGDH antibody

Alternative names for UGDH antibody

UDP-glucose 6-dehydrogenase, UDP-Glc dehydrogenase, UDP-GlcDH, UDPGDH

SwissProt ID

O60701 (Human), O70199 (Rat), O70475 (Mouse), P12378 (Bovin)

Gene ID

7358 (UGDH), 281564, 22235 (Ugdh), 83472

Ncbi ID

9606, NP_003350, NP_776636, NP_001171629.1, NM_003359, NP_001171629, NM_001184700, NP_033492.1, NM_009466, NM_031325, NM_001184701

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit), Ye (Yeast), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Dot blot (Dot), Immunodiffusion (ID), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Radioimmunoassay (R), Paraffin Sections (P)

Background of UGDH antibody

UDP-GlcDH (also called UDP-glucose 6-dehydrogese, UGDH or UDPGDH) is a member of the UDP-glucose/GDP-mannose dehydrogese family. UDP-GlcDH converts UDP-glucose to UDP-glucuronic acid, which is a crucial component in the biosynthesis of the glycosaminoglycans, hyaluron, heparan sulfate and chondroitin sulfate. Found as common components of the extracellular matrix, these glycosaminoglycans are significant in sigl transduction, cell migration, cancer growth and cancer metastasis. UDP-glucuronic acid (UDP-GlcA) is needed in the liver for the excretion of toxic compounds. UDP-GlcDH is a ubiquitously expressed protein most abundant in the liver. The protein structure of UDP-GlcDH was first alyzed in cow liver and found to be a homohexamer. This structure is well conserved between species and phyla with an overall 97% sequence identity shared between different species of mammals. Research indicates that UDP-GlcDH expression is upregulated by TGF? and downregulated by hypoxia.

General readings

Bontemps Y., et al. (2003) J Biol Chem. 278(24):21566-75.
Vatsyayan J., et al. (2006) Biosci Biotechnol Biochem. 70(2):401-10.

H00007358-B01P - UGDH
UGDH MaxPab polyclonal antibody. Western Blot analysis of UGDH expression in human liver.
H00007358-B01P - UGDH
Western Blot analysis of UGDH expression in transfected 293T cell line (H00007358-T01) by UGDH MaxPab polyclonal antibody.Lane 1: UGDH transfected lysate(54.34 KDa).Lane 2: Non-transfected lysate.
H00007358-B01P - UGDH
UGDH MaxPab polyclonal antibody. Western Blot analysis of UGDH expression in MCF-7.
AR09548PU-L - UGDH
Recombinant human UGDH, 1-494 aa, His-tagged
C19458-1 - UGDH
Western blot analysis of extracts from COLO cells, using UGDH Antibody. The lane on the right is treated with the synthesized peptide.
ARP61247_P050 - UGDH
Human HepG2; WB Suggested Anti-UGDH Antibody. . Titration: 1.0 ug/ml. . Positive Control: HepG2 Whole Cell. UGDH is supported by BioGPS gene expression data to be expressed in HepG2.; UGDH antibody - C-terminal region (ARP61247_P050) in Human HepG2 cells using Western Blot
AP54453PU-N - UGDH
UGDH Antibody (C-term) (AP54453PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of UGDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
AP54453PU-N - UGDH
UGDH Antibody (C-term) (AP54453PU-N) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the UGDH antibody detected the UGDH protein (arrow).
TP302132 - UGDH
TA314662 - UGDH
Western blot analysis of extracts from COLO cells, using UGDH antibody.The lane on the right is treated with the synthesized peptide.
TA326998 - UGDH
Western blot analysis of HepG2 cell and HeLa cell lysate using UGDH antibody.
TA326998 - UGDH
Immunohistochemistry of paraffin-embedded rat kidney using UGDH antibody at dilution of 1:200 (400x lens).
TA326998 - UGDH
Immunohistochemistry of paraffin-embedded human esophageal cancer using UGDH antibody at dilution of 1:200 (400x lens).
TA326998 - UGDH
Immunofluorescence analysis of HeLa cell using UGDH antibody. Blue: DAPI for nuclear staining.
TA343136 - UGDH
Host: Rabbit; Target Name: Ugdh; Sample Tissue: Rat Stomach lysates; Antibody Dilution: 1.0 ug/ml

2 Item(s)

per page

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ugdh (GFP-tagged) - Mouse UDP-glucose dehydrogenase (Ugdh), 200 uL, >10^7 TU/mL
Lenti ORF particles, Ugdh (GFP-tagged) - Mouse UDP-glucose dehydrogenase (Ugdh), 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Ugdh (Myc-DDK-tagged) - Mouse UDP-glucose dehydrogenase (Ugdh), 200 uL, >10^7 TU/mL
Lenti ORF particles, Ugdh (Myc-DDK-tagged) - Mouse UDP-glucose dehydrogenase (Ugdh), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.
 

2 Item(s)

per page

Active Filters

  1. Remove This Filter Product Type: Mouse Lenti ORF Particle
Clear All Filters

Available Filters

Manufacturer
  1. OriGene Technologies (2)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
© Copyright 1998 - 2018 OriGene Technologies GmbH
  • LinkedIn